Leukaemia

Question 1

What are the types of leukaemia?

Answer 1

There is Acute myeloid leukaemia - this is the most common form of leukaemia in adults
Acute lymphoblastic leukaemia - this is most common in children
Chronic myeloid leukaemia
Chronic lymphocytic leukaemia

Question 2

What is a leaukamia?

Answer 2

This is a blood cancer that usually begins in the bone marrow and results in a high number of blast cells

Question 3

What are the signs and symptoms of AML?

Answer 3

Marrow failure:
-anaemia
-infection - neutropenia
-bleeding
Infiltration:
-Hepatomegaly
-Splenomegaly

Question 4

What are the signs and symptoms of CML?

Answer 4

Insidious:
weight loss, tiredness, night sweats, fever
Anaemia
Bleeding
Splenomegaly

Question 5

What is the treatment for CML?

Answer 5

Imatinib is specifically targeted for CML

Then stem cell transplantation

Question 6

Wht are the signs and symptoms of ALL?

Answer 6

Usually seen in children:
Caused by bone marrow failure:
Anaemia - lethargy and pallor
Neutropenia - infections
Thrombocytopenia - easy bruising
Bone pain
Hepatosplenomegaly

Question 7

What is Richter’s transformation?

Answer 7

Ritcher’s transformation occurs when leukaemia cells enter the lymph node and change into a high-grade, fast-growing non-Hodgkin’s lymphoma. Patients often become unwell very suddenly.

Question 8

What are the signs and symptoms in CLL?

Answer 8

Enlarged non-tender, rubbery nodes

Hepatosplenomegaly