Lets gooooo Flashcards
Explain the dosing of hydrocortisone in patient with Addison’s
20mg at 8am and 10mg at 5pm to mimic the body’s natural variation in cortisol
Which bacterial infection can be complicated by sensioneural hearing loss?
Bacterial meningitis
Following a head injury, what criteria would indicate that a CT head should be undertaken in <1 hour?
More than one episode of vomiting
GCS < 13 on initial assessment
GCS < 15 at 2 hours post-injury
suspected open or depressed skull fracture
any sign of basal skull fracture (haemotympanum, ‘panda’ eyes, cerebrospinal fluid leakage from the ear or nose, Battle’s sign).
post-traumatic seizure.
focal neurological deficit.
Following a head injury, what criteria would indicate that a CT head should be undertaken in <8 hours?
age 65 years or older
any history of bleeding or clotting disorders including anticogulants
dangerous mechanism of injury (a pedestrian or cyclist struck by a motor vehicle, an occupant ejected from a motor vehicle or a fall from a height of greater than 1 metre or 5 stairs)
more than 30 minutes’ retrograde amnesia of events immediately before the head injury
Which antibiotic can be given antenatally to prevent necrotising enterocolitis?
erythromycin
What is Hereditary haemorrhagic telangiectasia?
genetic disorder
causes abnormal blood vessel formation in the skin, mucous membranes and often in organs such as the lungs, liver and brain.
Recurrent epistaxis (nosebleeds) are a common symptom because of the fragile blood vessels in the nasal lining.
What is Idiopathic thrombocytopenic purpura?
An autoimmune disorder where platelets are destroyed by antibodies leading to purpura (small red or purple spots caused by bleeding into the skin)
What is Peutz-Jeghers syndrome?
genetic condition causing the development of polyps in the digestive tract and hyperpigmented macules on lips, oral mucosa and digits.
What is the name given to the ocular sign where the pupil dilates when light is shone on it (and what condition is this associated with?)?
Marcus Gunn pupil- multiple sclerosis
What kind of crystals do you get in gout and psudogout?
Gout = Negatively birefringent needle-shaped crystals
Pseudogout = positively birefringent rhomboid-shaped crystals
What can be used to treat rosacea?
oral doxycycline and topical ivermectin
Which drug should be given to manage primary hyperaldosteronism due to bilateral hyperplasia of adrenal glands?
Spirnolactone
What are the 4 main causes of conn’s syndrome (primary hyperaldosteronism)
adrenal adenoma
adrenal hyperplasia
familial hyperaldosteronism
Adrenal carcinoma
What is the cause of secondary hyperaldosteronism?
Excess renin production from the juxtaglomerular cells
What causes the overproduction of renin in secondary hyperaldosteronism?
when the blood pressure detected by the juxtaglomerular cells is disproportionately lower than in the rest of the body
renal artery stenosis
renal obstruction
here failure (poor perfusion)
How can doctors differentiate primary and secondary hyperaldosteronism?
most common cause of otitis media?
haemophilus influenza
In those with otitis media, when SHOULD antibiotics be prescribed?
Symptoms lasting more than 4 days or not improving
Systemically unwell but not requiring admission
Immunocompromise or high risk of complications secondary to significant heart, lung, kidney, liver, or neuromuscular disease
Younger than 2 years with
bilateral otitis media
Otitis media with perforation and/or discharge in the canal
What is the z score in a dexa scan adjusted for?
age, gender and ethnic factors
What does a dexa z score measure?
your bone density to someone your age and body size.
What does a dexa T score measure?
bone mass
What is the dexa score associated with
1. Normal bone density
2. Osteopenia
3. Osteoporosis
> -1.0 = normal
-1.0 to -2.5 = osteopaenia
< -2.5 = osteoporosis
What blood marker can be used as an indicator of pancreatitis severity?
Hypocalcaemia
which tool identifies medications where the risk outweighs the therapeutic benefits in certain conditions?
STOPP tool