Lessons Flashcards

1
Q

During which week of development is the pronefrost scene?

A

Week 3

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2
Q

After development of the pronephros, what happens to it?

A

Degenerates

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3
Q

Which embryologic structure functions as an interim kidney during the first trimester?

A

Mesonephros

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4
Q

In males the mesonephros persists as which system?

A

Male Genital System

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5
Q

The wolffian duct forms which male structures?

A

Ductus deferens and epididymus

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6
Q

Which week of development is the metanephros scene?

A

5th week

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7
Q

Which week of Gestation is nephrogenesis completed?

A

Week 36

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8
Q

The Ureteric bud gives rise to which structures?

A

Ureter pelvises calyces and collecting ducts

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9
Q

Which week of gestation are the ureteric bud structures fully canalized?

A

Week 10

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10
Q

Interactions of which 2 tissues or structures induces the differentiation and formation of the glomerulus through the duct?

A

The metanephric mesenchyme and ureteric bud

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11
Q

Which structure in renal embryogenesis is the last to canalize?

A

The ureteropelvic junction

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12
Q

Which test can identify obstruction at the ureteropelvic junction?

A

Prenatal Ultrasound

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13
Q

What happens to the lungs in potter sequence ?

A

They are hypoplastic

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14
Q

What is the underlying pathology leading to the potter sequence?

A

Oligohydramnios

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15
Q

Cause of death in potter sequence

A

Pulmonary hypoplasia

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16
Q

What does the mnemonic potter stand for in the potter sequence?

A

Pulmonary Hypoplasia oligohydramnios, twisted face, twisted skin extremely defects and renal failure

17
Q

Some of the problems that can cause oligohydramnios leading to potter sequence?

A

Placental insufficiency or reduced renal output

18
Q

Some underlying causes of reduced renal output associated with potter sequence

A

Bilateral renal agenesis, obstructive uropathy and AR PKD

19
Q

Under which vessel do horseshoe kidneys get stuck upon ascent?

A

Inferior mesenteric artery, although mostly benign

20
Q

4 common problems associated with horseshoe kidney.

A

Hydronephronsis, renal stones, infection and an increased risk of renal cancer

21
Q

Type of chromosomal problems associated with a horseshoe kidney

A

Any type of chromosomal aneuploidy

22
Q

The presence of unilateral agenesis is a result of failure of which structure during development?

A

The ureteric bud

23
Q

Describe the pathophysiology underlying the development a multi-cystic dysplastic kidney.

A

The ureteric bud develop but fails to induce differentiation of metabolic mesenchyme

24
Q

Which 2 areas can lead to the formation of y-shaped bifid ureter

A

Bifurcation of ureteric bud before it enters the metanephric blasters or when two uroteric reach and interact with the metanephric blastema.

25
Q

2 conditions strongly associated with a duplex collecting system.

A

Vesico ureteral reflux, ureteral obstruction

26
Q

Which type of infection is associated with a duplex collecting system

A

UTIS

27
Q

How does a duplex collecting system typically present?

A

With hydronephrosis

28
Q

Posterior ureteral valves are remnants of which make structure?

A

They are membranous remnants of the prostatic urethra in males

29
Q

What are 2 findings on ultrasound that will allow you to diagnose posterior urethral valves.

A

Bilateral hydronephrosis and a dilated or thick wall bladder

30
Q

What is the most common cause of bladder outlet obstruction in male infants?

A

Posterior Uretheral valves

31
Q

In cases of severe obstruction, posterior urethral valves are associated with which findings?

A

Oligohydramnios

32
Q

What is the main risk associated with vesicoureteral reflux?

A

Recurring UTIS

33
Q

What is the main primary cause of vesicoureteral reflux?

A

Either abnormal or insufficient insertion of the ureter within the ureteral vesicle junction

34
Q

What is the most likely secondary cause of vesicoureteral reflex?

A

Abnormally high bladder pressure

35
Q

2 errors can lead to the formation a y-shaped bifid ureter

A

Bifurcation of the uroteric bud before it enters the metanephric blastema or 2 uroteric buds reach and interact with the metanephric blastema