Lesson 8 | Cerebrospinal fluid Flashcards

1
Q

One of the most commonly performed tests for CSF

A

Cerebrospinal Fluid Proteins

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2
Q

Normal value for CSF Proteins

A

15 - 45mg/dL

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3
Q

Major protein for CSF Protein

A

Albumin

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4
Q

2nd most prevalent CSF Protein

A

Prealbumin

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5
Q

Alpha-globulin

A

Haptoglobin
Ceruloplasmin

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6
Q

Major beto-globulin

A

Transferrin

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7
Q

Binds to iron in the blood

A

Transferrin

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8
Q

Gamma globulins

A

Primarily IgG
Small amounts of IgA

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9
Q

Carbohydrate-deficient transferrin fraction seen only in CSF

A

tau

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10
Q

Qualitative test for CSF Proteins

A

Nonne-Apelt
Rose-jonse
Pandy’s
Nogochi
Colloidal Gold test

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11
Q

Quantitative test for CSF Proteins

A

Turbidimetric
Automation
Dye-binding technique
Biuret method
Electrophoresis

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12
Q

For CSF Glucose, blood glucose should be drawn _____

A

2 hours before spinal tap

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13
Q

In CSF Glucose it compares ____

A

CSF and Blood glucose

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14
Q

Normal value of CSF Glucose

A

60-70% of plasma glucose

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15
Q

Decreased glucose values

A

Bacterial meningitis
Tubercular meningitis

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16
Q

Normal glucose values

A

Viral meningitis

17
Q

Increased glucose values

A

Diabetes
Encephalitis
Intracranial pressure

18
Q

Clinical uses of Lactate

A

Meningitis
Tissue destruction
Severe head injuries
False increase

19
Q

Product of bacterial metabolism

A

Lactate

20
Q

Normal value of CSF Glutamine

A

10-24mg/dL

21
Q

Range for bacterial meningitis

A

> 35mg/dL

22
Q

Range for viral meningitis

A

<25mg/dL

23
Q

CSF glutamine is produced by CNS by brain cells from

A

Ammonia and Alpha-ketoglutarate

24
Q

Increased in glutamine and ammonia

A

=brain damage

25
Q

Normal values of CSF glutamine

A

8-18 mg/dL

26
Q

Indirect test for the presence of excess ammonia of the CSF

A

CSF glutamine

27
Q

Increased lactate values in

A

Liver disorders
Reyse’s syndrome
Coma of unknown origin