Lesson 7 Flashcards

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1
Q

Front

A

Back

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2
Q

What is protein synthesis?

A

Protein synthesis is the process by which cells make proteins.

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3
Q

What are the roles of proteins?

A

Proteins function in transport, structure, enzymes, and protection.

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4
Q

What is the central dogma of genetics?

A

The central dogma is the flow of genetic information from DNA to RNA to protein.

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5
Q

What happens in transcription?

A

In transcription, DNA is transcribed into mRNA.

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6
Q

Where does transcription occur?

A

Transcription occurs in the nucleus.

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7
Q

What is mRNA?

A

mRNA is a messenger RNA that carries genetic information from the DNA to the ribosome.

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8
Q

Where does translation occur?

A

Translation occurs in the cytoplasm on the ribosome.

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9
Q

What is tRNA?

A

tRNA is transfer RNA that carries amino acids to the ribosome during protein synthesis.

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10
Q

What is the role of ribosomes?

A

Ribosomes are the site of protein synthesis where mRNA is translated into amino acid chains.

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11
Q

Define codon.

A

A codon is a sequence of three nucleotides in mRNA that corresponds to a specific amino acid.

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12
Q

What is the start codon?

A

The start codon is AUG, which codes for methionine.

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13
Q

What are stop codons?

A

Stop codons are UAA, UAG, and UGA, signaling the end of translation.

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14
Q

What is translation?

A

Translation is the process by which mRNA is translated into a polypeptide chain of amino acids.

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15
Q

What is the role of amino acids in proteins?

A

Amino acids are the building blocks of proteins and determine the structure and function of the protein.

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16
Q

What are mutations?

A

Mutations are changes in the DNA sequence that can affect protein synthesis.

17
Q

Explain the wobble hypothesis.

A

The wobble hypothesis suggests that the third base of a codon can be flexible, allowing multiple codons to code for the same amino acid.

18
Q

What is a ribosome made of?

A

A ribosome is made of rRNA and proteins, and has three sites: A-site, P-site, and E-site.

19
Q

Explain the process of denaturation in protein synthesis.

A

Denaturation is the process where the protein structure is altered, usually due to heat or chemicals, causing it to lose function.

20
Q

How does a mutation affect protein synthesis?

A

A mutation can change the amino acid sequence, leading to a non-functional or malfunctioning protein.

21
Q

What is the role of the spliceosome?

A

The spliceosome removes introns (non-coding regions) from mRNA before it is translated.

22
Q

How do stop codons work in translation?

A

Stop codons signal the end of the translation process, causing the ribosome to release the synthesized protein.

23
Q

Explain the importance of the 5’ cap and 3’ poly-A tail in mRNA processing.

A

The 5’ cap and 3’ poly-A tail protect the mRNA from degradation and assist in its export from the nucleus.

24
Q

How does translation differ in prokaryotes and eukaryotes?

A

In prokaryotes, translation occurs simultaneously with transcription, whereas in eukaryotes, transcription happens in the nucleus and translation in the cytoplasm.

25
Q

How does the ribosome move along mRNA during translation?

A

The ribosome moves along the mRNA from 5’ to 3’, reading the codons and forming peptide bonds between amino acids.