Lesson 6

Question 1

what does tablet provide ?

Answer 1

An accurate, stable dose of drug

Question 2

Pros and cons of tablet ?

Answer 2

Pros:
- easy to use, less expensive
- physically, chemically stable
- convinence in production, storage, transport

Cons:
- difficulties in swallow
- preparing is impractical

Question 3

Granulation is nescessary for :

Answer 3

Granulation step is often necessary to:  Maintain content uniformity
 Give acceptable flow properties
 Avoid particle segregation
 Assure physical and chemical stability  Improve compactability

Question 4

what does binder use for?

Answer 4

Binders are adhesive materials used to hold powders together to form granules and assist in holding the tablet together after compression with adequate hardness.

Question 5

In wet- granulation process how does type and concentration of binder affect ?

Answer 5

Affect granule strength, friabilithy, granule growth rate

Question 6

What does particle size and size distribution affect ?

Answer 6

affect flow, compressibility

Question 7

what does densification affect ?

Answer 7

affect rate of drug release