Lesson 2: Respirator System, Mediastinum And Pleura Flashcards

1
Q

Conductive system

A

Nostrils
Nasal cavity
Paranasal sinuses
Nasopharynx
Larynx
Trachea
Extrapulmonary bronchi
Intrapulmonary brunchi

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2
Q

Transitional system

A

Bronchioles

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3
Q

Secretory cell of transitional system

A

Club cell/ clara cell

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4
Q

Serve as transition zone between the conductive system and gas exchange system

A

Bronchioles (primary, secondary, thirtiary)

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5
Q

Highly metabolic and play an important role in detoxification of xianobitics

A

Club/ clara cell

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6
Q

Protein secreted by clara cell

A

Collectin

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7
Q

Exchange system

A

Alveoli ( alveolar duct, atrium,alveolar sac, alveolus)

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8
Q

System of gas exchange is superficially line by__?

A

Pneumonocytes l (membranous)
Pneumonocytes ll (granular)

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9
Q

Respiratory system vulnerability to aerogenous injuries is primarily due to:

A
  1. Extensive interface between the respiratory system and inspired air.
  2. Large volume of air that continuously passing in to the lungs.
  3. High concentration of noxious element that can be present in the air.
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10
Q

Normal flora of respiratory tract are restricted only in what particular part?

A

Conductive system (nasal cavity, pharynx and larynx)

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11
Q

Conducting system is lined by what particular type of cell?

A

Pseudo stratified collumnar ciliated epithelium ( nasal cavity, paranasal sinuses, part of the larynx, all of trachea and bronchi)

Olfactory epithelium (ethmoidal conchae)

Squamous epithelium (nasal vestibulum, part of the larynx)

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12
Q

Cell of the respiratory system which lines most of the nasal cavity, nasopharynx, part of larynx, trachea and bronchi.

A

Pseudo stratified ciliated epithelium

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13
Q

What will happen if the ciliated cell become irreversibly injured due to viral infection, or inhalation of toxic gases.

A

Ciliated cells swell, lose their attachment to underlying basement membrane.

Transient and mild exudate of fluid,plasma proteins, and neutrophils covers the ulcer.

Specific type of progenitor cell known as basal cells or non nucleated secretory present in the mucosa migrate to cover the denuded basement membrane and undergo mitosis.

Eventually differentiating into new ciliated epithelial cell

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14
Q

Respiratory cell that quite resistant to all form of injury.

A

Squamous epithelium

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15
Q

Under normal circumstances, cellular exfoliation is prompt fallowed by:

A

Inflammation
Mitosis
Cell proliferation
Cell differentiation
Repair

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16
Q

This is form of chronic bronchitis is well illustrated in habitual smokers who continually need to cough excessive mucus secretion. ( production of mucus secretion is increased via goblet cell hyperplasia)

A

Chronic catarrhal inflammation

17
Q

One of the most devastating sequelae to chronic remodeling of the bronchi, it consists of pathologic and permanent dilation of the bronchus with rupture of the bronchial as a result of obstruction or chronic inflammation.

A

Bronchiectasis

18
Q

Degradation and weakening of smooth muscle and cartilage

A

Chondromalacia

19
Q

Further sequelae to bronchiolar metaplasia and mucous hypersecretion blocking or partially blocking the lumen of these bronchioles.

A

Pulmonary emphysema
Atelactasis

20
Q

Pulmonary disease in horses in which Pulmonary emphysema and atelactasis are two of the defects manifestation.

A

Chronic obstructive pulmonary disease/ recurrent airway obstruction “ heaves”

21
Q

Sequelae of bronchiolar injury

A

-Emphysema
-Atelectasis
-Hyperresponsiveness airway disease
-Recurrent airway obstruction

22
Q

It develops in human and animal after a transient and innocuous viral infection of the lower respiratory tract from exposure to certain allergies.

A

Hyperresponsiveness airway disease

23
Q

These two types of alveolar fibrosis are most commonly seen in toxic and allergy pulmonary diseases and have a devastating effect on lung function.

A

Alveolar septal fibrosis
Intraalveolar fibrosis

24
Q

The most common route in the transmission of most respiratory infection in domestic aniy.

A

Aerogenous

25
Q

some viruses, bacteria, parasites, and toxins can enter the respiratory system via the circulating blood.

A

Hematogenous

26
Q

Pathogenic organisms can also reach the pleura and lungs thru penetrating injuries.

A

Direct extension

27
Q

Process by which particles os various sizes, shapes are traped within specific region of respiratory tract.

A

Deposition

28
Q

Process by which deposited particles are destroyed, neutralized, and removed from the mucosal surfaces.

A

Clearance

29
Q

Main mechanisms involve involve in clearance:

A

Sneezing
Coughing
Absorption
Mucociliary transport
Phagocytosis

30
Q

Difference between what is deposited and what is cleared from the respiratory system.

A

Retention

31
Q

The physical removal of deposited particles or dissolved gases from the respiratory tract.

A

Mucociliary clearance

32
Q

Main defense mechanism of conducting system.

A

MUCOCILIARY CLEARANCE

Antibodies
Lysozyme
Mucus

33
Q

The main defense mechanism of alveoli

A

Phagosytosis

34
Q

Inflamation of the nasal musuosarhini

A

Rhinitis