Lesson 2: membrane and lipid diversity and symmetry Flashcards
What are the 3 major categories of Membrane lipids
- Glycero-phospholipids
- Shingolipids
- Galacto-lipids
What are the components that make up Glycero-phospholipids
Backbone: glycerol
Alkyl chains: 2 fatty acids chains
Polar head group: phosphate
X -group: alcohol
What are the components that make up a Shingolipid (Phospholipid)
Backbone: sphingosine
Alkyl chain: 1 FA chain
Polar head group: phosphate
X group: choline
What are the components that make up a Shingolipid (Glyoclipids)
Backbone: Sphingosine
Alkyl chain: single FA chain
Polar Head: mono/ oligosaccharide
X group: none
What are the components that make up Galactolipids (aka sulfolipid)
Major Group: Glycolipids
Backbone: glycerol
Alkyl chains: 2 FA chains
Polar head: mono/disaccharide
X- group: sulphate (SO4)
What are the systematic and common name of the
Fatty Acid: 12:0
Systematic: n-Dodecanoic acid
Common name: Lauric acid
12 = laur_
What are the systematic and common name of the
Fatty Acid: 14:0
Systemic: n-tetradecanoic acid
Common: Myristic
14 = Myris
What are the systematic and common name of the
Fatty Acid: 16:0
Systemic: n-hexadecanoic acid
Common: palmitic acid
16= palm
What are the systematic and common name of the
Fatty Acid: 18:0
Systematic: n-octadecanoic acid
Common: stearic acid
18= stear
What are the systematic and common name of the
Fatty Acid: 20:0
Systematic: n- Eicosanoic acid
Common: Arachidic acid
20 = eicosanic
10=decanoic
What are the systematic and common name of the
Fatty Acid: 24:0
Systematic: n-tetraeicosanoic acid
Common: Lignoceric acid
Wood
What are the systematic and common name of the
Fatty Acid: 16:1 (delta*9)
Systematic: cis-9-hexadecanoic acid
Common: Palmitoleic acid
What are the systematic and common name of the
Fatty Acid: 18:1 (delta*9)
Systematic: cis-9-octadecanoic acid
Common: Oleic acid “oil”
What are the systematic and common name of the
Fatty Acid: 18:2 (delta*9,12)
Systematic name: cis-,cis-9,12-Octadienoic acid
Common: Linoleic acid “Greek linon- flax”
What are the systematic and common name of the
Fatty Acid: 18:3 (delta*9,12,15)
Systematic: cis-,cis-,cis-9,12,15-Octadecatrienoic acid
Common: alpha-linolenic acid
What are the systematic and common name of the
Fatty Acid: 20:4 (delta*5,8,11,14)
Systematic: cis-, cis-,cis-,cis-5,8,11,14-Eicosatetraenoic acid
COMMON: Arachidonic acid
What are the 3 connections between IRDS and Membrane Biochemistry
- Surfactant is composed of phospholipids
- Surfactant reduces surface tension of alveolar fluid
- Surfactant allows the alveoli to expand and exchange gases b/w air and fluid