FCPS Pearls 2

Question 1

Actin binds to Z disc via

Answer 1

Actinin protein

Question 2

Actin binds to Z disc via

Answer 2

Actinin protein

Question 3

Cross-bridge in sarcomere of skeletal muscles are made up of

Answer 3

Myosin

Question 4

Phases of action potential cycle in atria, ventricles and Purkinje fibers

Answer 4

1. Phase 0 - Depolarization
2. Phase 1 - Initial repolarization
3. Phase 2 - Plateau
4. Phase 3 - Rapid repolarization
5. Phase 4 - Resting membrane potential

Question 5

Phases of action potential cycle in SA node

Answer 5

1. Phase 0 - Upstroke
2. Phase 1 and 2 - Absent
3. Phase 3 - Repolarization
4. Phase 4 - Slow depolarization

Question 6

Heart ventricles decreased upstroke is due to

Answer 6

Prolonged opening of Na channels

Question 7

Regarding Cat-electrotonic potential

Answer 7

All or none potential

Question 8

About astrocytes action potential

Answer 8

Action potential is generated with increased intracellular potassium

Question 9

Cytoskeleton to ECM

Answer 9

Integrin

Question 10

Cytoskeletal ECM to ICM

Answer 10

Intermediate filament

Question 11

ECM to ICM

Answer 11

Integrin

Question 12

Cell to cell adhesion

Answer 12

Cadherin

Question 13

Firm adhesions are by

Answer 13

LFA-1 > integrin

Question 14

Transient adhesions are mediated by

Answer 14

Selectins

Question 15

Desmosomes are made up of

Answer 15

1. Cytokeratin
2. Cadherin
3. Intermediate filaments

Question 16

If a drug molecular weight is less than 100 Da, transport occurs via

Answer 16

Diffusion

Question 17

If a drug molecular weight is 100 Da or more, transport occurs via

Answer 17

Pinocytosis

Question 18

Primary active transport vs secondary active transport

Answer 18

Primary AT requires ATP
Secondary AT requires electrochemical gradient

Question 19

Fructose is absorbed in intestine via

Answer 19

Facilitated diffusion

Question 20

Glucose and amino acids are absorbed in duodenum and jejunum via

Answer 20

Active transport

Question 21

Chloride is absorbed in PCT by

Answer 21

Passively by electrochemical gradient

Question 22

Glucose is absorbed in the kidney via

Answer 22

Secondary active transport

Question 23

Glucose and amino acids are absorbed in PCT via

Answer 23

Active transport

Question 24

The diffusion capacity of pulmonary capillaries increases in (normal and abnormal)

Answer 24

1. Increase in alveolocapillary surface area
2. Polycythemia

Question 25

Types of cells on the basis of their dividing capabilities

Answer 25

1. Labile cells
2. Stable cells
3. Permanent cells