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Cell physiology > FCPS Pearls 1 > Flashcards

FCPS Pearls 1 Flashcards

1
Q

Mitochondria are increased in

A

Ciliated cells

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2
Q

Mitochondria are absent in

A

Red blood cells

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3
Q

Polychromasia meaning

A

Increased immature red blood cells in the bloodstream

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4
Q

Nissl bodies are

A

Discrete clumps of RER and ribosomes in nerve cells

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5
Q

Nissl bodies are present in which cells

A

Neurons

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6
Q

Tay Sach’s disease clinical features

A

Blindness and mental retardation

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7
Q

Tay Sach’s diasease cause

A

Deficiency of lysosomal enzyme Hexosaminidase A

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8
Q

Pompe disease cause

A

Deficiency of lysosomal alpha glucosidase enzyme

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9
Q

Alcohol detoxification occurs by

A

Peroxisomes

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10
Q

Neutrophils produce bactericidal agents (Reactive oxygen species) by which organelle

A

Peroxisomes

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11
Q

Receptors for tyrosine kinase are present in

A

Cell membrane

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12
Q

Endotoxin present in bacteria are part of

A

Outer cell membrane

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13
Q

Signs of reversible cell injury

A
  1. Cellular swelling
  2. ER swelling
  3. Myelin figures
  4. Ballooning or hydropic changes due to mitochondrial injury
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14
Q

Signs of irreversible cell injury

A
  1. Karyolysis
  2. Karyorrhexis
  3. Pyknosis
  4. Necrosis
  5. Apoptosis
  6. Autophagy of cells
    7.Massive Ca2+ influx
  7. Large mitochondrial densities
  8. Cellular shrinkage
  9. Cytoplasmic blebs
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15
Q

Irreversible cell injury sign in MI

A

Contraction bands in cytoplasm

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16
Q

The central factor in the pathogenesis of irreversible cell injury

A

Membrane damage

17
Q

Which protein is utilized by skeletal muscles during relaxation?

A

Tropomyosin

18
Q

Diazepam relaxed skeletal muscles by acting on

A

Internuncial neurons

19
Q

The metabolic response of skeletal muscles in trauma is

A

Increased proteolysis

20
Q

Main constituents of atherosclerotic plague

A
  1. Smooth muscles
  2. Extracellular matrix
  3. Extracellular and intracellular lipids

Cell physiology (3 decks)

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