Lesson 1 Flashcards
What are commensals
acquired soon after birth, are able to adhere to body
surface
can exist as a commensal in the rumen but when it
transfers to the liver of feedlot cattle it can act as a pathogen that causes hepatic
abscesses.
Fusobacterium necrophorum
What is pathogen?
Compete with normal flora to foothold in the niche, bring disease to the host
Capacity of the pathogen to produce a disease
Pathogenicity
virulence
The degree of pathogen to produce a disease.
Virulence factors
Adhesins
Capsule
Toxin
Genes encode virulence factors
Plasmid
Bacteriophages
Pathogenicity Island
Animals become infected of their own bacteria (microrlora) /..when the
bacteria gain access to sites from which they are usually absent.
Endogenous infection
What is exogenous infection?
direct or indirect transmission of pathogen from an
infected animal or from the environment
main portals of entry of infection
Mucosae of the
gastrointestinal Respiratory tract
Urogenital tract
Pathogen- host interaction
determined by the virulence of the bacteria and by the effectiveness of the host
response.
Two categories of pathogen that are able to survive in a host.
Obligate intracellular pathogen
Facultative intracellular pathogen
Example of obligate intracellular pathogen
Chlamydiae
Rickettsiae
Example of facultative intracellular pathogen.
Mycobacterium sp.
Brucella sp.
Salmonella sp.
Major virulence factor
Adhesins
Capsule
Toxins
Use by pathogen to attach to host tissues and to resist the flushing action of body fluids
Adhesins