Leshmania Flashcards
1
Q
Leshmania
A
Unicellular protozoa I’m 2 forms
- Amastigote (non-motile, in mammals)
- Promastigote (motile, in insect vector)
2
Q
Vector
A
Sand fly (phlebotomus app)
3
Q
Reservoir host
A
Dogs, other mammals and rodents
4
Q
Leishmania causes
A
LEISHMANIASIS
5
Q
Visceral leishmaniasis
A
L. Donovan - kalaazar Travels to internal organs - liver - spleen - bone marrow Leading to organomegaly (hepatosplenomegaly)
MOST SEVERE - fatal
6
Q
Cutaneous leishmaniasis
A
L. Tropica
- Enters phagocytes via receptor mediated phagocytosis
- Establishes a parasitophorous Vacoule
- Survives inside by delaying phagosome maturation