LES Flashcards

1
Q

Qual o principal vírus associado ao desencadeamento do LES?

A

Epstein-Barr

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2
Q

Hormônio sexual com característica imunoestimulante

A

Estrogênio

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3
Q

Relação do tabagismo e o LES

A

desenvolvimento do autoanticorpo Anti-DNA

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4
Q

As quatro principais classes de autoanticorpos

A

Antinucleares
Anticitoplasma
Antimembrana
Antifosfolipideo

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5
Q

Principais autoanticorpos antinucleares relacionados ao LES (6)

A

Anti-DNA
Anti-histona
Anti-SM
Anti-RNP
Anti-LA (SS-B)
Anti-Ro (SS-A)

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6
Q

autoanticorpos mais especificos para o LES (2)

A

Anti-SM
Anti-DNA

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7
Q

autoanticorpo presente obrigatoriamente do lupus farmacoinduzido

A

Anti-histona

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8
Q

autoanticorpos presente na sindrome de Sjogren

A

anti-LA (SS-B) e anti-Ro (SS-A)

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9
Q

autoanticorpo anticitoplasma

A

anti-P

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10
Q

o anti-P se relaciona com quais manifestações lúpicas?

A

manifestações neuropsiquiatricas

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11
Q

Principais autoanticorpos antimembrana relacionados ao LES (4)

A

antilinfócito, antineurônio, antiplaqueta, antihemácias

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12
Q

principal manifestação dos anticorpos antifosfolipideos

A

formação de trombos

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13
Q

Principais autoanticorpos antifosfolipideo relacionados ao LES (3)

A

anticoagulante lupico
anti-Beta2glicoproteína 1
anticardiolipina

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14
Q

caracteristica do anticoagulante lupico

A

alargamento do TTPa in vitro; porém in vivo promove coagulação

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15
Q

anticorpo de triagem lupica

A

FAN

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16
Q

critério de entrada para diagnóstico de LES segundo EULAR/ACR 2019

A

FAN + (> 1:80)