LES Flashcards

1
Q

Autoanticuerpos

A
ANAS
Anti-DNA
Anti-Ro Anti-La
anticuerpos anti-celulas endoteliales
Anti-Sm
antineuronales
anti-nucleosomas
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2
Q

Manifestaciones clínicas

A

Fiebre, perdida apetito, perdida de peso, perdida cabello, artralgias, mal estado general, fatiga, rash malar, dolor torácico

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3
Q

problemas hematologicos

A

anemia normocítica
trombocitopenia
linfopenia
leucopenia

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4
Q

manifestaciones cutáneas

A
eritema malar
livedo reticularis
vasculitis necrotizante
fotosensibilidad
alopecia
mucinosis
fenomeno de raynaud
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5
Q

¿qué fármacos se deben evitar?

A
sulfas
penicilina
procainamida
ibuprofeno
isoniacida
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6
Q

Tto piel

A

Hidroxicloroquina
dapsone
talidomida
retinoides

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7
Q

tto articular

A
AINES
hidroxicloroquina
acetaminofen
propoxifeno
metotrexate
amitriptilina
corticoides dias alternos
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8
Q

tto nefritis lúpica

A

leve: azatioprina
moderada: MMF o CFM, mantenimiento con azatioprina
severa: Euro-Lupus CFM 1.5mg cada 15 días x 3 meses.

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8
Q

tto nefritis lúpica

A

leve: azatioprina
moderada: MMF o CFM, mantenimiento con azatioprina
severa: Euro-Lupus CFM 1.5mg cada 15 días x 3 meses.

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9
Q

terapia biológica

A

Belimumab. una IgG1 monoclonal que actúa en el BLyS o BAFF

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10
Q

Pacientes de alto riesgo

A
sexo masculino
raza negra
compromiso renal
afección neurológica
afección cardiovascular
dosis altas de esteroides
anticuerpos antifosfolipídicos
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11
Q

En la orina se encuentra:

A

Hematuria
Leucocituria
Proteinuria
Cilindros celulares

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