Legionnaires Disease Flashcards

1
Q

Signs and symptoms

A

Muscle aches, headache, fever, cough, shortness of breath, chest and abdominal pain, diarrhea, vomiting

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2
Q

Causative agent

A

Legionella pneumophila, a Gram negative bacterium that stains poorly in clinical specimens

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3
Q

Pathogenesis

A

Organism multiplies within phagocytes; released with death of cell; necrosis of cells lining the alveoli; inflammation and formation of multiple small abscesses

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4
Q

Epidemiology

A

Originates mainly from warm water contaminated with Protozoa such as found in air conditioning systems

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5
Q

Treatment and prevention

A

Treatment: antibiotics
Prevention: avoiding the contaminated water aerosols; regular cleaning and disinfection of humidifying devices

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