Lectures Flashcards
Where are neuropeptides produced?
In presynaptic cells.
What are neuropeptides?
Neurotransmitters or - modulators produced in nerve cells with very specific targets.
Are neuropeptide receptors exclusively specific receptors?
No. They mostly only bind teir ‘own’ peptide-transmitters but can partially react with others too.
Whats’s the difference between analgesic and anti-nociceptic agents?
The former prohibits pain sensation, the later the development of tissue damage (?).
What opioid receptors does morphine act upon?
μ-opioid receptors (MOR).
Cannabinoid receptor - what type of receptor is this?
GPCR.
Are all hair cells of the otic organ sensing cells?
No. Only one cell is connected to the auditive nerve, wuilst the rest are supporting cells.
Distinguish between nocsic and nociceptic.
Nocsic: causes tissue damage
Nociceptic: message about tissue damage
What does sensoric-discriminative pain sensation pervey?
Place, time and strength.
What does affective-motivational pain sensation pervey?
The ‘emotion’ of pain.
Distinguish between clinically different types of pain (3).
Nosiseptic, neuropathic and psycogenic.
What related the secondary, slow pain response?
C-polymodal nociceptor. Emits chemical signals that a) increase blood vessle permeability and b) signsl the occurence of damage. Activated by certain bacteria as such (sans intermediate messengers).
What receptor mediates ‘fast’ pain?
A-δ deep nociceptor.
What is motoric equivalence?
The ability to perform the same task (e.g. task) with different motor systems (right hand, left hand, wrist immobilised, using the mouth).
Outline the three basic types of movement.
a) reflexive
b) rhythmic actions (e.g. walking)
c) wilful motor function
