Lectures 1-4 Flashcards

1
Q

Economic evaluation is a broad term and captures

A
Cost-effectiveness analysis (CEA)
►Cost utility analysis
►Cost minimization analysis
►Cost benefit analysis
►Net monetary benefit analysis
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2
Q

Providers

A

Role: improve patient health
►Value: ensure the intervention offers best clinical value to patient
►Relates to comparative effectiveness research

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3
Q

Hospitals

A

Role: improve patient health
►Value: provide best clinical value to patient and make a strong value proposition
►Consider example of robotic-assisted surgery

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4
Q

Insurers

A

Role: improve patient health within budgetary limits

►Value: ensure patients receive best value

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5
Q

Government

A

Role: Improve patient health and use policies to incentivize value
►Value: Maximize health within budgetary limits

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6
Q

Patients

A

Role: Improve their health

►Value: Best clinical value that they can afford

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7
Q

Nongovernmental organizations

A

Role: How to measure value and incentivize optimal allocation
►Value: Defines, assesses, and constructs policies to promote value

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8
Q

Manufacturers

A
Product pricing (“value for money”)
►Marketing strategy
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9
Q

Third party payers (health insurers)

A
Coverage decisions (new therapies, drugs, devices...)
►Payment decisions (provider reimbursement, patient cost-sharing)
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10
Q

Medical professional organizations

A

Practice guidelines

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11
Q

Health systems (hospitals)

A

Management tools (control cost while maintaining quality)

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12
Q

intervention

A
An intervention is a ”choice” we will evaluate in economic evaluation
It represents a change in health care practice that aims to either improve health or reduce costs
►Drugs
►Surgery techniques
►New technology
►Screening strategy
►Public health campaign
►New process or structure of care
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13
Q

Resources

A
Resources can represent a variety of inputs
►Resources can be
►Time
►Labor
►Capital
►Technology
►We can think of these resources in terms of money such that we have a common unit
►Remember, time = money
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14
Q

Opportunity cost

A

Opportunity cost = value of what we are giving up to acquire a resource

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15
Q

Market Prices

A


Market prices is the result of demand meeting supply

Buyers have varying willingness to pay for a specific good

Sellers have varying willingness to sell a specific good (function of quantity)

Where these meet determines market clearing price

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16
Q

Imperfect Market of Health Care

A

The health care market is imperfect for many reasons including:
1.Buyers often rely on agents for purchasing health care
●Doctor prescribing drugs or treatments
2.Information about prices is not widely available
●What insures pay is often hidden
3.Price is rarely negotiated
4.Price and demand is often subsidized by insurance
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17
Q

Medical costs

A

Direct cost for medical goods and services

►For example, cost of drugs or surgical procedures

18
Q

Morbidity costs

A

Any nonmedical costs associated with the morbidity of a condition
►Often opportunity costs
►For example, lost wages due to illness

19
Q

Mortality costs

A

►Any nonmedical costs associated with the mortality of a condition
►Often opportunity costs
►For example, lost wages due to illness

20
Q

Other nonmedical costs

A

Nonmedical costs associated with an illness that are not captured by the above
►Often direct costs such as transportation cost

21
Q

Payment transfers

A

Costs associated with the payment or receipt of money due to an illness

22
Q

Micro-Costing Approach

A

►Micro costing is used to estimate the cost of a health intervention
►As the name suggests, it estimates each individual components cost
►Three stages of micro-costing:
►Identification of all resources involved in the provision of care (e.g., human-resources, time, and supplies)
►Measurement of each resource (for example using time-and-motion studies)
►Valuation of the resources used

23
Q

Burden of Disease Studies

A

Takes into account:
►Morbidity of disease (time disabled or sick)
►Mortality of disease (time lost due to premature death)
►Often source of information for economic evaluation modeling and decision analysis

24
Q

Cost-Effectiveness/Utility Analysis (CEA/CUA)

A

Examines two or more alternative activities (interventions)
►Single, common outcome that differs only in magnitude between the alternative activities
►Results are expressed as a ratio of differences in cost and differences in effects

25
Cost-Effectiveness Analysis (CEA)
CEA outcome (effects) measured in “natural units” ►Life-years, gain in life expectancy ►Clinically relevant outcomes (e.g., Hg for blood pressure; HbA1c for diabetes, etc.) ►Infections averted; number of diseased patients, or symptom-free days
26
Cost-Utility Analysis (CUA)
CUA outcome (effect) based on individual or societal preferences (utilities) ►Outcome measured in quality‐adjusted life years (QALYs), disability‐adjusted life years (DALYs), or Healthy years equivalent (HYE) ►Outcomes capture both quality and quantity of health
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Disadvantages to CEA and CUA
Cannot be used to compare interventions beyond the health sector (i.e., costs can be directly compared, but outcomes cannot) ►May not capture inter-health sector comparisons completely ►Some health interventions have other outcomes which must be explicitly listed as inputs to the decision-making process ►Requires studies to estimate utility (for QALY measurement) or disability weights (for DALY measurement) ►Theoretical controversies and measurement issues in the field 8
28
Theory behind Economic Evaluation
The principle aim of economic evaluation is to maximize societal health for a given budget ►Maximization requires optimal allocation ►Utilize the intervention with the best value first before utilizing the next intervention ►Microeconomics underpins much of economic evaluation ►Multiple theories within microeconomics
29
Decision analysis:
a quantitative method for choosing from a set of alternatives under conditions of uncertainty
30
Model
a representation of some real-world phenomena, object, or behavior
31
Cohort study
A cohortis a group of people related in some way (e.g., socio-economic and demographic characteristics): e.g., a birth cohort is a cohort of people born within a given time period ►Researchers can compare outcomes between members of the cohort exposed to the intervention and those not exposed
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Case-control study
►Compares subjects who have an outcome of interest (cases) with subjects who do not have the outcome (controls) ►Looks back retrospectively to compare how frequently the exposure to a risk factor is present in each group to determine the relationship between the risk factor and the outcome
33
Markov Models
State-transition models ►Assume finite numbers of health states (Markov states) ►Patients assigned to one and only one state at a given time ►Patients can transition between states based on some state transition probabilities ►Transition probabilities can be time-dependent (e.g., chance of death increases with age, independent of health) ►The probabilities of moving from one state to all other possible states must always add up to 1 ►Highly flexible and allow for an infinite variety of diseases or interventions to be simulated and understood ►Most popular tools for public health and health care research 5