Lecture exam flashcards
The ability of a specific target cell to respond to a hormone is dependent on __________.
the specific extracellular or intracellular receptor that binds to the hormone
What specific molecules are secreted by cells and function to alter or regulate target-cell metabolism?
Hormones
Most amino acid-based hormones exert their effects on target cells through the activation of intracellular __________.
second messengers, like cyclic AMP
Which of the following is NOT involved in stimulating the release of hormones from endocrine glands?
The action of one hormone opposing the effect of another hormone on the surface of a target cell.
Which of the following is NOT a factor that affects target-cell activation following hormone-receptor interaction?
Synthesis of regulatory molecules within the target cell
Steroid hormones alter target-cell activity by __________.
binding to hormone response elements on chromatin to initiate protein synthesis via gene expression
Why do hormones cause an amplification effect on target cells, causing them to elicit multiple metabolic responses?
This occurs because activated protein kinases catalyze many reactions, which phosphorylate many molecules.
Thyroid-stimulating hormone (TSH) is a water-soluble hormone. Which statement BEST describes how TSH causes target-cell activation?
TSH indirectly activates G-proteins, causing the synthesis of intracellular second messengers.
Human blood includes all of the following components EXCEPT:
Interstitial fluid
Which of the following is a regulatory function of blood?
Maintaining pH balance of body fluids
What is the average normal pH range of blood?
7.35 - 7.45
Erythrocytes can be described by all of the following EXCEPT:
They can easily replicate themselves in the blood supply.
Which of the following is a protective function of blood?
Preventing blood loss from damaged vessels
What are the fragments of megakaryocytes that function in hemostasis?
Thrombocytes
A platelet plug forms when __________.
thrombocytes release chemicals causing them to aggregate at the site of damage on a blood vessel
Which statement is FALSE about monocytes and neutrophils?
They are granulocytes produced via hemopoiesis.
Which sequence correctly identifies the order of events necessary for blood coagulation?
Formation of prothrombinase –> Prothrombin converts to thrombin –> Fibrinogen converts to fibrin
All of the following are functions of the lymphatic system EXCEPT:
Delivering respiratory gases to the body cells
Which statement BEST describes lymph transport in the lymphatic system?
Chyle is a specific type of lymph that transports digested fats.
Which statement is TRUE about lymphatic cells and lymphatic tissue?
Every immunocompetent T cell and B cell responds to a specific antigen, which is why self-tolerance is important in their maturation.
Which lymphatic structure is NOT composed of reticular connective tissue?
Thymus
Antibodies that respond to viruses and toxins are synthesized and released by __________.
plasma cells
Which statement is TRUE regarding differences between lymphatic capillaries and blood capillaries?
Lymphatic capillaries are more permeable than blood capillaries due to their flap-like minivalves.
How does age affect the size of the thymus?
The thymus increases in size after birth, then decreases in size from adolescence through old age.
Which lymphatic structure drains lymph directly into the venous blood of the left subclavian vein?
Thoracic duct
Which statement is FALSE regarding the spleen?
The spleen traps bacteria in crypts, which are invaginations in the splenic tissue.
The MOST abundant formed elements in the blood are, whereas are the LEAST abundant formed elements in the blood.
erythrocyte & basophils
Name one specific steroid hormone:
estrogen
Name one specific eicosanoid:
leukotrienes
The specific plasma protein involved in the final phase of blood coagulation is.
fibinogen
During B cell activation, antibodies are synthesized and secreted from , and destroy the antigens marked by antibodies.
plasma cells
One specific lymphatic structure located in the pharynx of the oral cavity is the.
palatine tonsil
Blood coagulation is one example of hemopoiesis
False
Lymph forms from interstitial fluid surrounding the lymphatic capillaries.
True
Type O- blood lacks A, B, and Rh antigens on the surfaces of the erythrocytes
True
Calcitonin and parathyroid hormone exhibit a synergistic effect at their target cells
False
Each erythrocyte can carry up to four molecules of oxygen.
False
What is the tough, superficial layer of the pericardium that helps prevent overstretching of the myocardium?
fibrous pericardium
The __________ function(s) to reduce friction between the parietal and visceral layers of the serous pericardium.
pericardial fluid
Which statement is TRUE about the myocardium of the heart wall?
The myocardium is innervated by autonomic neurons, which control heart contractions and heart rate.
Which event does NOT occur when the semilunar (SL) valves are open?
Ventricles are in diastole, and atria are in systole.
Veins of the coronary circulation can be described by all of the following EXCEPT:
These vessels carry oxygenated blood to the left atrium of the heart.
The myocardial thickness of the left ventricle is necessary in order to __________.
pump blood into the aorta with greater force and pressure
When is the tricuspid valve (right AV valve) closed?
during ventricular systole
Deoxygenated blood pumped from the right ventricle into the pulmonary trunk will enter the __________.
pulmonary circulation
Which statement BEST describes a unique characteristic of autorhythmic fibers?
These cells have gap junctions that allow them to act as a functional syncytium.
Which statement is TRUE regarding arteries?
Elastic arteries function under high blood pressure to stretch rapidly as blood leaves the heart.
Which statement BEST describes the tunica externa (tunica adventitia) of a vein?
The tunica externa is the thickest layer of the venous wall composed of collagen and elastic fibers.
What process involves the passive movement of oxygen molecules down a concentration gradient out of the blood?
Diffusion
All of the following factors affect blood flow EXCEPT:
a decrease in arterial pressure caused by atrial diastole
Which statement correctly identifies one structural difference between arteries and veins?
Arterial walls are composed of a thick layer of smooth muscle fibers, whereas venous walls are not.
Located in the kidneys, __________ are microscopic blood vessels with small pores through their endothelial walls.
fenestrated capillaries
Which statement BEST describes blood flow?
Blood flow through the entire systemic circulation is equivalent to cardiac output.
Which tunic of arterial walls has the greatest effect on blood flow and blood pressure?
Tunica media
Which statement is FALSE regarding capillary blood pressure?
Capillary blood pressure constantly fluctuates due to ventricular systole.
How is pulse pressure calculated?
Systolic pressure minus Diastolic pressure
Which statement is TRUE regarding the effect of vascular resistance?
Vascular resistance increases as blood viscosity increases.
Which statement BEST describes the process of filtration across capillary walls?
Filtration involves a positive pressure difference between the hydrostatic pressure and colloid osmotic pressure.
The blood vessels that deliver blood directly into capillary beds are called __________.
arterioles
Which statement is TRUE regarding systemic blood pressure?
An increase in erythrocyte production may cause an increase blood pressure.
All of the following factors aid in the venous return of blood EXCEPT:
smooth surface of the endothelium
__________ circulation functions to drain deoxygenated blood from the digestive viscera into the liver.
Hepatic portal