Lecture (Exam 1) Flashcards
Chemical Level
Atoms and Molecules
Cellular Level
Cell: Basic structural and functional unit of life
Tissue Level
Tissue: Similar cells that perform a common function
Organ Level
Organ: 2 or more kinds of tissues integrated to perform specific funtions
Organ System Level
Organ System: Organs having related functions
Organismal Level
Organism: Has several organ systems which work together to maintain life.
Sagittal
Divides the body or organ into unequal right or left portions
Midsagittal
Divides the body or organ into equal halves
Coronal (Frontal)
Divides the body or organ into anterior (front) and posterior (back) portions
Transverse (Horizontal, Cross-Sectional)
Divides the body or organ into superior (top) and inferior (bottom) portions.
Medial
Closer to midline
Lateral
Away from the midline
What does Cephalad mean?
Head
Cephalic Region?
Head
Orbital Region?
Eye
Nasal Region
Nose
Buccal Region
Cheek
Oral Region
Mouth
Mental Region
Chin
Cranial Region
Area covered by the scalp
Name for Neck?
Cervix
What is the Cervical Region?
The Neck
What is the Thorax or Thoracic Region?
Chest
Pectoral Regions
Left and Right Chest
Mammary Regions (Breasts)
Sit atop pectoral regions
Sternal Region
Between pectoral regions; overlies sternum
Axillary Regions
Armpits
Abdominal Region
Located between the diaphragm and the top of the hip bones
Pelvic Region
Between the hip bones
Deltoid Region
Shoulder
Brachial Region
Arm; Between shoulder and elbow
Antecubital (Cubital) Region
Front of elbow
Antebrachial Region
Forearm
Carpal Region
The “wrist”
Manus (Hand) Region
The Hand
Palmar
Front of hand
Dorsum
Back of hand
Femoral Region
Thigh
Patellar Region
Front surface of knee
Popliteal Region
Back of the knee (slightly indented)
Crural Region
Leg; between knee and ankle
Tarsal Region
Ankle
Petal Region
Foot
Plantar
Sole
Dorsum
Top Surface
Cranial Cavity
Brain resides here
Vertebral Cavity
Spinal cord resides here
Thoracic Cavity
Chest Cavity
Pleural Cavity
A lung resides in each
Mediastinum
Cavity between lungs
Pericardial Cavity
(within mediastinum) contains the heart
Abdominal Cavity
From thoracic diaphragm to top of hip bones
Pelvic Cavity
Between the hip bones
Plasma Membrane
Surrounds cell, forms a limiting barrier between external and internal environments
Structure of Plasma Membrane?
2 Layers of Phospholipids containing cholesterol and proteins
Plasma Membrane - Proteins
They’re in the membrane and they’re loosely attached to the surface
Plasma Membrane - Glycoproteins
Proteins with carbohydrates attached
Plasma Membrane - Glycolipids
Phospholipids with carbohydrates attached
Plasma Membrane - Permeable
Determined primarily by size, charge, and solubility of molecule. Regulates movement of material in/out of cell.
Plasma Membrane - Functions - Passive Transport
Simple Diffusion: Movement of substances through the cell membrane based on concentration differences (high to low)
Active Transport
Movement of substances through the cell membrane against a concentration gradient
Exocytosis
Process by which large molecules are secreted from the cell. Materials packaged within vesicles. Vesicles fuse with cell membrane and release contents outside of cell.
Endocytosis
Process by which large molecules are brought INTO the cell
Phagocytosis
“Cel Eating”: Engulfment of large particles with membrane extensions
Pinocytosis
“Cell Drinking”: Indigestion of fluid and small particles
Receptor-mediated endocytosis
Substances bind to receptor which stimulates the formation of an nvagination and a vesicle is internalized
Microvilli
Nonmotile; Help increase the SA
Cilia
Motile, move substances over the surface of stationary cell
Flagellum
Motile, whip like structure that moves cells.
Mitochondrion
Produce ATP. We break a Phosphate away to make it ADP. When reasting, Mitochondrion adds the phosphate back to make ATP
Ribosomes
Involved in protein production (syntheis)
Free Ribosomes
Makes proteins for the cell
RIbosomes attached to the ER…
make proteins primarily for export
Endoplasmic Reticulum
Network of tubules used to transport and synthesize (produce materials)
ROugh Er
Has ribosomes on walls. TRansports and modififes proteinsmade by ribosomes.
Smooth ER
Has no ribosomes. Synthesizes lipids, mainly steroids. Detoxify drugs and alcohol.
Golgi Apparatus
Composed of flattened cisternae which modify and package proteins. Package proteins for secretion and forms lysosomes.
Lysosomes
Contains digestive enzymes. Enzymatically breaks down internalized material and old organelles. Fatal cytosis is when you bring it in.
Centrioles
Needed for cell division (two pairs)
Nucleus
Contains a Nuclear Envelope. It has nuclear pores and is selectively permeable.
Nucleolus
Made up of RNA, enzymes, and other proteins
What happens when a cell isn’t dividing?
DNA can be found associated with proteins in a filamentous mass. (Chromatin)
DNA
It is made up of nucleotides (each consists of phosphate, sugar, and base)
Shape of DNA?
Double Helix
Prior to Cell Division…
The DNA “unzips”. Free nucleotides will attach to the parent strand (=template). Each new DNA molecule consists of one parent strand and one new strand = replication
What is responsible for protein production?
Ribosomes
Cell Cycle is divided into how many phases?
Two phases
Interphase
Cell is not dividing. DNA is replicated during this time.
Mitosis
Mitosis (Cell division for somatic cells) or Meiosis (cell division for sex cells)
When is DNA replicated?
During Interphase
Mitosis - Step One
Prophase
Prophase
- Chromatin (DNA and Proteins) becomes supercoiled to form chromosomes.
- Chromosomes are double stranded DNA. Two chromatids joined by a centromere.
- Nuclear membrane and nucleolus break down!
- Spindle fibers extend from centrioles to the chromosomes
Mitosis - Step Two
Metaphase
Metaphase
Chromosomes align along center of cell
Mitosis - Step Three
Anaphase
Mitosis - Step Four
Telophase
Anaphase
- The two chromatids split apart at centromere
2. Each chromatid, a single stranded chromosome, is pulled to opposite ends of cell
Telophase
- Single chromosomes uncoil
- Nuclear envelope and nucleolus reforms
- Ckeavage furrow develops. (Indent in chromosome)
What occurs after Telophase?
Cytokinesis
What is Cytokinesis?
Division of cytoplasm. Cells now enter Interphase. Without this, they would have two nuclei in a cell.
In which of the following stages of mitosis do the centromeres split and the chromatids begin to separate?
Anaphase
What is Histology?
Microscopic study of tissues
Four kinds of tissues?
Epithelia, Connective, Muscle, Tissue
Location of Epithelia?
Covers body/organ surfaces, lines body cavities and forms glands
Characteristics of Epithelia?
Very Cellular
Has a free surface (apilcal surface)
Bound to underlying tissue by a basement membrane
Avascular (Vessels that lack blood)
Epithelia Layer Options?
Simple Epithelium
Stratified Epithelium
Simple Epithelium
One layer thick
Stratified Epithelium
Many layers thick
Epithelia Shape options?
Squamous
Cuboidal
Columnar
Squamous
Flattened Cells
Cuboidal
Cube-Shaped Cells
Columnar
Hexagonal Column
What are Simple Squamous Epithelium?
One layer of flattened cells
Simple Squamous Epithelium Location?
Lines lumen (cavity) of blood vessels, tiny air sacs of lungs, and lines body cavity
Simple Squamous Epithelium Function?
Primarily rapid diffusion and filtration (Thinnest of all tissues)
Simple Cuboidal Epithelium
One layer of cube-shaped cells
Simple Cuboidal Epithelium Location
Lines tubules (salivary glands and kidneys). (Thicker so its not used for rapid diffusion and filtration)
Simple Cuboidal Epithelium Function
Secretion and Absorption
Simple columnar Epithelium
One layer of tall, narrow cells. May have microvilli, goblet cells, or cilia.
Simple Columnar Epithelium Location
Lines most of GI (Gastrointestinal Tract)
Simple Columnar Epithelium Function
Secretion (Mucus and Enzymes) and Absorption (Nutrients)
Pseudostratified Columnar Epithelium
Single layer of cells with varying heights that appears multilayered. One kind has cilia (pseudostratified CILIATED columnar epithelium) and goblet cells
Types of Simple Epithelia
Simple Squamous Epithelium
Simple Cuboidal Epithelium
Simple Columnar Epithelium
Pseudostratified Columnar Epithelium
Types of Stratified Epithelia
Stratified Squamous Epithelium
Transitional Epithelium
Pseudostratified Columnar Epithelium Location
Lines most of respiratory tract
Pseudostratified Columnar Epithelium Function
Protection (moving dirty mucus) and Secretion (mucus)
Stratified Squamous Epitherlium
Upper layer of cells are flattened, lower layers appear cuboidal or polyhedral. Deepest layers highly mitotic.
Types of Stratified Squamous Epithlium?
Keratinized and Nonkeratinized
Keratinized Stratified Squamous Epithelium
Contains keratin, superficial layers consist of dead cells
Keratinized Stratified Squamous Epithelium Location
Epidermis
Keratinized Stratified Squamous Epithelium Function
Protection (Protects by making thick barrier to keep things in and out)
Nonkeratinized Stratified Squamous Epithelium
Superficial cells are alive and keep moist
Nonkeratinized Stratified Squamous Epithelium Location
Oral Cavity, Part of Pharynx, Esophagus, Vagina, and the Anus.
Nonkeratinized Stratified Squamous Epithelium Function
Protection
Transitional Epithelium
Some cells are binucleated. Surface cells may be done shaped or flattened.
Transitional Epithelium Location
Found in most of the urinary tract
Transitional Epithelium function
Withstands distention (stretching) and relaxing
Glandular Epithelia
Specialized epithelial tissues that have excretory functions.
Exocrine Glands
Formed from epithelial tissues - they secrete their materials onto a free surface.
Types of Exocrine Glands?
Unicellular
Multicellular
Unicellular Exocrine Glands
Goblet Cells
Unicellular Exocrine Glands Location
Respiratory and digestive systems.
Unicellular Exocrine Glands Function
Secrete mucus!
Multicellular Exocrine Gland Types
Merocrine Glands
Apocrine Glands
Holocrine Glands
Merocrine Glands
Secretes a watery fluid through the cell membrane.
Merocrine Gland Example
Salivary Glands. You constantly make and release it
Apocrine Glands
Top part of the cell is pinched off, it becomes the secretion. Stored at very top of the cell. Have to release the tip to be released by the rest of the body.
Apocrine Gland Example
Mammary Glands
Holocrine Glands
Entire cell is released and it ruptures and dies. They produce oil. Cell release and in the duct, it breaks apart releasing oil.
Holocrine Gland Example
Sebaceous (Oil) Gland
Which epithelial tissue allows primarily for rapid filtration and diffusion?
Simple Squamous
Characteristsics of Connective Tissue
Binds/Supports/Protects other tissues and organs, derived from mesenchyme (Embryonic CT)
Connective Tissue consists of
Cells
Extracellular Matrix
Vascularity Varies
Connective Tissue - Cells
Tons of cells. Typically unattached space between cells.
Connective Tissue - Extracellular Matrix.
Outside of the cells, the space between the cells.
Whats located in the Extracellular Matrix?
Fibers which include…
Collagen
Elastin
Reticular
Ground Substance
Collagen used for
Strength
Elastin used for
Elasticity
Reticular used for
Support
What is Ground Substance?
Reticular fiber in this. Extra cellular matrix suspended in ground substance.
What does Vascularity Vary?
Some don’t have blood cells.
Classifications of Connective Tissues
Connective Tissue Proper - Gel Like
Cartilage - Semisolid
Bone - Rigid
Vascular Tissue - Liquid
Connective Tissue Proper
Matrix is gel-like
What falls in Connective Tissue Proper?
Loose CT
Dense CT
Loose Connective Tissue contains
fewer fibers, more ground substance
Dense Connective Tissue contains
more fibers, fewer ground substance
What falls under Loose Connective Tissue?
Areolar CT
Adipose (Fat Tissue)
Areolar CT
Predominant cells are fibroblasts, many irregularly arranged fibers and it’s very vascular (blood vesels)
Areolar CT Location
Surrounds nerves, vessels, and muscle cells
Areolar CT Function
Packing and binding material (artery to vein)
Adipose (Fat Tissue)
Contains adipocytes (it’s very vascular)
Adipose Location
Primarily in the skin
Adipose Functions
Stores fat (energy), insulation against temperature changes, an protection (Absorbs Shock)
What falls under Dense CT
Dense Irregular CT
Dense Regular CT
Dense Irregular CT
Contains fibroblasts: Irregularly arranged bundles of collagen (very vascular)
Dense Irregular CT Location
Dermis (Lower level of skin)
Dense Irregular CT Function
Withstands stress in all directions
Dense Regular CT
Contains fibroblasts; protein fibers are arranged in parallel bundles. Poor vascularity.
Dense Regular CT Location
Tendons and Ligaments
Dense Regular CT Function
Strength and Flexibility (In One Direction)
Cartilage
Semisolid Matrix. Avascular (No Blood Vessels)
Flexible
Heals Slowly
Cells = Chondroblasts (Can heal) and Chondrocytes (Maintain the cartilage)
Cells In Lanunae
What falls under Cartilage?
Hyaline Cartilage
Fibrocartilage
Elastic Cartilage
Hyaline Cartilage
Matrix contains very fine collagen fibers (Almost impossible to see them)
Hyaline Cartilage Location
Found on articular surfaces (ends of bones)
Nasal Septum
Tracheae
Fetal Skeleton
Function of Hyaline Cartilage?
Support and Protection
Fibrocartilage
Matrix contains thick collagen fibers
Fibrocartilage Location
Found in intervertebral disks
Symphysis pubis
Menisci
Function of Fibrocartilage?
Withstands compression and absorbs shock
*Compress and spring back to normal shape; basically shock absorbers
Elastic Cartilage
Matrix contains numerous elastic fibers.
Elastic Cartilage Location
Outer Ear and Larynx (Voice Box)
Function of Elastic Cartilage?
Flexibility and Strength
Bone
Matrix is rigid and it’s highly vascularized.
Types of bone tissue within bones?
Compact (Dense)
Spongy (Cancellous)
Compact Bone
Outer shell of bone
Spongy Bone
Inner lattice-work of bone.
Hemopoietic (red bone marrow) tissue found within spaces
Vascular Tissue (Blood)
Contains blood cells (or formed elements) and a liquid matrix called plasma
Function of Vascular Tissue (Blood)
Transport (Nutrients, Materials, Hormones)
Muscle Tissue
Moves body and materials within the body
Types of Muscle Tissue?
Smooth Muscle Tissue
Cardiac Muscle Tissue
Skeletal Muscle Tissue
Shape of Smooth Muscle Tissue?
Spindle-Shaped Cells (Thick in middle and tapers at the end)
Nucleus in Smooth Muscle Tissue?
One centrally location nucleus
Smooth Muscle Tissue Voluntary or Involuntary?
Involuntary
Where is Smooth Muscle Tissue Found?
Found in walls of hollow organs
Shape of Cardiac Muscle Tissue?
Short, Cylindrical or Bifurcated branching Cells
Nucleus in Cardiac Muscle Tissue?
Has one or TWO centrally located nuclei
Special feature of Cardiac Muscle Tissue?
Has Intercalated Discs (ICD is a masas of protein that holds cells together so that they don’t separate)
What distinguished Cardiac Muscle Tissue?
Striations
Are Cardiac Muscle Tissue Voluntary or Involuntary?
Involuntary
Skeletal Muscle Tissue Shape?
Long, Cylindrical Cells
Nucleus in Skeletal Muscle Tissue?
Nuclei located periphery of cell
Distinguishing feature of Skeletal Muscle Tissue
Striations
Are Skeletal Muscle tissues Voluntary or Involuntary?
Voluntary
Nervous Tissue
Makes up the nervous system
Types of Nervous Tissue Cell Types?
Neurons Supporting Cells (Neuroglia)
Neurons
Generate and Conduct Nerve Impulses
Supporting Cell (Neuroglia)
Support, protect, and nourish neurons