lecture 9 - learning and memory Flashcards
what is procedural memory
unavailable to the conscious mind
what is declarative memory
available to conscious mind
what is explicit memory
memory consciously recalled
eg. getting a present
what is implicit memory
cant be recalled
eg. learning to ride a bike
what are the advantages of using snails, worms and insects to study the neuronal basis of learning
big neuronal size
less complex circuits
no temperature dependance
What are the 3 forms of memory studied
habituation
sensitisation
associative learning
what is habituation, give an example
decrease in response
eg. eye blink reflex
describe habituation in the gill withdrawal reflex of aplysia
sensory neuron activates motor neuron 7 , which activates gill muscle, so withdrawal
what will we see in Vm in habituation of pre, post and inbetween synapses
pre- see change in pre
post/inbetween- no change in Vm of pre
what is the cellular basis of habituation
reduced transmitter release from presynaptic neuron
continued stimulation leads to RRP (type of vesicle) decrease
what is sensitisation, give an example
increase in response
eg. touching someone with sunburn will hurt more
describe the synaptic transmission of sensitisation
2 sensory neurons synapse to motor neuron
one of these releases seratonin which activates g alpha s
pkA produced
phosphorylates and inactivates K+ channels
this means longer depolarisation so more vesicle release
what is an example of associative learning
weak siphon touch paired with a strong shock
what is the cellular mechanism for associative learning
Ca2+ influx increases seratonin effect
what is the difference between early and late stages of associative learning
early- glutamate receptor pathways work together
late- gene expression can alter glutamate receptors
