Lecture 9: Diuretics Flashcards
1
Q
List the drug classes of Diuretics (6)
A
- Carbonic Anhydrase Inhibitors
- Osmotic Diuretics
- High-Ceiling Diuretics (Loop Diuretics)
- Thiazide
- K+ sparing diuretics (Aldosterone antagonists, Epithelial Na+ channel inhibitors)
- Vasopressin Antagonist
2
Q
Which drug(s) are Carbonic Anhydrase Inhibitors?
A
Acetazolamide
3
Q
Which drug(s) are Osmotic Diuretics?
A
Mannitol
4
Q
Which drug(s) are High-Ceiling Diuretics (Loop Diuretics)?
A
Furosemide
- Strongest with fluid retention
- K+ wasting
5
Q
Which drug(s) are Thiazide?
A
- Hydrochlorothiazide
- Chlorthalidone
K+ wasting
6
Q
Of the drug(s) that are K+ sparing diuretics, which are
- Aldosterone antagoinst
- Epithelial Na+ channel inhibitors
A
- Aldosterone antagoinst: Spironolactone
- Epithelial Na+ channel inhibitors: Triamterene
7
Q
Which drug(s) are Vasopressin Antagonist?
A
Conivaptan
H2O more than Na+
8
Q
List the sections of the kidney that partake in reabsorption
A
- Proximal tubule
- Thin descending/ascending loop
- Thick descending loop
- Distal convoluted tubule
- Cortical collecting tubule
- Medullary collecting duct
9
Q
1 of 6
What substances are reabsorbed in the proximal tubule? (5)
A
- NaHCO3
- NaCl
- Glucose
- Organic acid and bases
- Amino acids
10
Q
2 of 6
What substances are reabsorbed in the thin descending/ascending limb?
A
- H2O (descending limb)
11
Q
3 of 6
What substances are reabsorbed in the thick ascending limb? (5)
A
- K+
- Ca2+
- Mg2+
- Cl-
- Na+
Low H2O perm.
