lecture #9

Question 1

Opium is from

Answer 1

opium poppy seeds

Question 2

opium is a mixture of chemicals with the most prevalent being _____ , __________

Answer 2

morphine and codeine

Question 3

derivatives of opium are known as

Answer 3

opioids

Question 4

heroin

Answer 4

derivative of morphine by acetylation

Question 5

buprenorphine

Answer 5

partial agonist, lessens euphoric effects

Question 6

Methadone

Answer 6

opioid that behaves like heroin but with less euphoric effects and long acting

Question 7

chronic pain

Answer 7

5th vital sign

Question 8

abuse is

Answer 8

used for the feeling to get high

Question 9

tolerance

Answer 9

effect of drug wears off, need more for the same effect

Question 10

dependence has two types

Answer 10

psychological dependance cravings
physiological: withdrawal upon cessation.

Question 11

what is hyperalgesia

Answer 11

heightened sensitivity to pain that occurs from opioid use

Question 12

addiction

Answer 12

compusive use, despite harm

Question 13

clinical effects of opioids

Answer 13

contains opoid receptors in the cerbral cortex for pain relief and medulla for euphoria (respiratory depression

Question 14

potency is not as important as dose

Question 15

dose rate importance example

Answer 15

oxycontin not meant to be chewed or crushed. need to reformulate into uncrushable

Question 16

Naloxone

Answer 16

antidote for opioid sandoz, teva, perrigo competitive antagoism

Question 17

opioid withdrawal syndromes

Answer 17

piloerection (goose flesh) chills, V/N

Question 18

OWS can be treated with

Answer 18

methadone, buprenophrine

Question 19

small volitable products that makes distilled drinks distinct

Question 20

clinical effects of ethanol

Answer 20

abosptive, toxic, elimination

Question 21

legal limit

Answer 21

80 mg/dL

Question 22

drunk?

Answer 22

BAC via breath analyzer + FST

Question 23

how alcohol affects CNS

Answer 23

1. change the fluid components of menbrane, haldane effect
2. inhibits GABA receptor chloride channel complex

Question 24

sedatives

Answer 24

GABA chloride channel

Question 25

melleby effect

Answer 25

acute tolerance tachyphylaxis

Question 26

conventional benxo

Answer 26

xanax, valium

Question 27

NPS benxo

Answer 27

etizolam

Question 28

roofies

Answer 28

flunitrazwpam

Question 29

special K

Answer 29

euhjpria, deep CNS depression

Question 30

carisoprodol soma

Answer 30

muscle relaxant

Question 31

sedative intoxication

Answer 31

mostly coma

Question 32

antidote

Answer 32

flumazenil