Lecture 9 (1/3) Flashcards
what is a syndrome?
a collection of signs, symptoms, and medical problems that tend to occur together, but are not related to a specific, identifiable cause
- can turn into a disease or collection of disease
- you don’t know the cause
what is a disease?
a medical condition with a specific cause or causes and recognizable signs and symptoms
what is cancer?
whole bunch of individual diseases
what are the 3 types of clinical pain?
- acute pain
- cancer pain
- chronic non-cancer pain
difference between acute, sub-acute, and chronic pain
- acute: if back pain get resolved in 6-7 weeks
- Sub-acute: longer than that but less than 3 months
- Chronic: more than 12 weeks
why are there two phases of postsurgical pain?
there’s nociceptors activated at cut and from inflammation after you wake up
explain the role of analgesics after surgery
Analgesic wont reduce nociceptive output, but it might reduce inflammation post surgery
who is Scott Reuben?
published series of papers stating preemptive analgesia makes pain better, but he was a fraud (now no one believes preeemptive analgesia was a thing)
when does post-surgical pain become chronic post-surgical pain?
when it doesn’t go away after 3 months
in the USA, how many operations per year are there and how many develop CPSP?
23 million operations per year (5-85% develop CPSP)
what is causing CPSP?
Almost certainly that surgeon nicked the nerve (neuropathic pain)
Why doesn’t the risk of developing CPSP appear in surgical consent forms?
Not the surgeon’s problem (they don’t deal with pain)
explain the grey matter and CPSP study
- If you successfully treat pain, grey matter comes back
- No one knows what’s causing grey matter loss, nor which part of the brain is losing grey matter
what is primary cancer?
where it starts
what are the most likely and least likely types of cancer to be painful?
- least: leukemia
- most: oral/bone cancer
