Lecture

Question 1

tight junctions

Answer 1

prevent leakage between cells

Question 2

adherens junctions

Answer 2

join actin of one cell to actin of neighboring cell

Question 3

desmosome

Answer 3

joins intermediate filaments in one cell to those in a neighbor

Question 4

gap junction

Answer 4

small water-soluble ions and molecules pass through

Question 5

hemidesmosome

Answer 5

anchors intermediate filaments in a cell to the basal lamina

Question 6

itchy

bullous pemphigoid or pemphigus vulgaris

Answer 6

bullous pemphigoid

Question 7

painful

bullous pemphigoid or pemphigus vulgaris

Answer 7

pemphigus vulgaris

Question 8

vitilago MOA

Answer 8

AI

Question 9

Wood’s light

Answer 9

fluorescence = depigmented skin

Question 10

melasma MOA

Answer 10

often hormonal change

Question 11

primary causes of EM

Answer 11

HSV

mycoplasma pneuomoniae

Question 12

kaposi - classic

Answer 12

lower legs +/- edema

Question 13

HHV8

Answer 13

kaposi

Question 14

erythema nodosum causes

Answer 14

idiopathic
sarcoid
strep 
OCP
TB
inflamm bowel

Question 15

rapid onset and hand involvement

Answer 15

acanthosis nigricans

Question 16

ring worm

Answer 16

tinea

Question 17

jock itch

Answer 17

tinea

Question 18

athletes foot

Answer 18

tinea

Question 19

snake like

Answer 19

tinea- “ring worm”

Question 20

edge-active

Answer 20

tinea

where fungus is most abundant

Question 21

___ require oral antifungals

Answer 21

tinea capitis
tinea folliculitis
onychomycosis

Question 22

azoles and ____ are active against both dermatophytes and candida

Answer 22

ciclopirox

Question 23

why is tinea versicolor a misnomer?

Answer 23

caused by yeast not dermatophytes

Question 24

fawn color

polycyclic border

Answer 24

tinea versicolor

Question 25

lichen planus: immuno rxn of ____ along basal layer of epidermis

Answer 25

helper T cells

Question 26

Wickham’s striae

Answer 26

lichen planus

oral white lines

Question 27

parkinsons
HIV
DM
epilepsy
neuroleptic

assoc

Answer 27

seborrheic dermatitis

Question 28

hs of eczema w no resolution

Answer 28

cutaneous T cell lymphoma

Question 29

skin cancer w highest incidence

Answer 29

basal cell CA

Question 30

Bowen’s diseae

Answer 30

SCC in situ

slow growing
flat w/ silvery scale
well demarcated

Question 31

keratoacanthoma

Answer 31

SCC variant

rapidly growing
low met risk
spontaneous remission

Question 32

corticosteroid immuno targets

Answer 32

inhibit..
NF-kB
TNF-a
cycloocygenase
adhesion molecules

Question 33

corticosteroid AE

Answer 33

skin atrophy
steroid acne
glaucoma, cataracts
worsened cutaneous infec
allergic contact dermatitis
poss systemic sx

Question 34

wet rashes

Answer 34

lotion/gel

Question 35

shave biopsy

Answer 35

epi and part of derm

for BCC, SCC

Question 36

punch biopsy

Answer 36

all 3 layers plus subQ fat

• any pigmented lesion
• rash
• eruption

Question 37

ephilid vs solar lentigo

Answer 37

ephilid –> small, brown, sun exposed skin, fades w UV abstinence

solar lentigo –> tan patch, photo distribution, older pt

Question 38

inc activity of melanocytes along basal layer

Answer 38

solar lentigo

Question 39

lesser trelat sign

Answer 39

tons of seborrheic keratoses all at once

Question 40

button hole sign

Answer 40

if poked, skin indents and NEUROFIBROMAS are slow to pop back up

Question 41

Dermatitis herpetiformis is a chronic, intensely _____, vesicular disease

Answer 41

pruritic

Question 42

An ___ workup is appropriate with facial molluscum contagiosum involvement in adults.

Answer 42

HIV

suggest pt is immune compromised

Question 43

Melanocytic nevi are tan to brown macules or papules that often first appear in _____

Answer 43

childhood

Question 44

HHV7

Answer 44

pityriasis rosea