Lecture 8 Sex, hormones, and happiness Flashcards

1
Q

Age-related changes affecting sexual wellness

A

Normal aging does decrease sexual/reproductive efficiency and lengthens sexual response times:

  1. Degenerative changes in all reproductive organs.
  2. Diminished levels of sex hormones: Estrogen in women; testosterone in men - but this decline is more variable in men.
  3. Cessation of menses and loss of reproductive ability in women; older men have variable reproductive ability.
  4. Altered response to sexual stimulation.
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2
Q

Risk factors that affect sexual function - societal influences

A
  1. Myths of aging; attitudes about aging and sexuality.
  2. Cultural beliefs; Kinsey Reports - public displays of affection, orgasms, etc.
  3. False perceptions, self-fulfilling prophecy.
  4. Stigmatization of homosexual individuals.
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3
Q

Risk factors that affect sexual function - individual influences

A
  1. Limited opportunities - erectile dysfunction, lack of a partner, social circumstances, lack of privacy, etc.
  2. Adverse effects of medications, nicotine, and alcohol.
  3. Functional impairments - arthritis, COPD, incontinence.
  4. Chronic illnesses - dementia, diabetes, heart disease, depression, BPH, etc.
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4
Q

Medications for erectile dysfunction (ED)

A
  1. Sildenafil (Viagra).

2. Tadalafil (Cialis).

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5
Q

Sleep apnea is a risk factor for impaired sexual function because it results in _

A

Hypertension.

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6
Q

Medications that cause disorders of desire include _

A
  1. Psychoactive medications - antipsychotics, benzodiazepines, barbiturates, lithium, and all SSRIs.
  2. Hormonal agents.
  3. Cardiovascular medications - beta blockers, calcium channel blockers, thiazide diuretics, hydralazine, etc.
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7
Q

Medications that cause disorders of arousal include _

A
  1. Anticholinergics (Levodopa).
  2. Antihistamines (Benadryl, Claritin).
  3. Antihypertensives.
  4. Psychoactive medications - SSRIs, MAOIs (Nardil), benzodiazepines, tricyclic antidepressants.
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8
Q

Medications that cause disorders of orgasm include _

A
  1. Amphetamines and related anorexic drugs.
  2. Antipsychotics.
  3. Methyldopa.
  4. Narcotics.
  5. SSRIs.
  6. Trazodone.
  7. Tricyclic antidepressants.
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9
Q

With the exception of _ and _, all antidepressants can cause erectile dysfunction.

A
  1. Trazodone.

2. Bupropion (Wellbutrin).

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10
Q

In men, chronic use of alcohol affects production of _ and _ and can cause impotence and reduced libido.

A
  1. Testosterone.

2. Gonadotropin.

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11
Q

Regarding sexuality, cigarettes and nicotine are linked with the development of _

A

Erectile dysfunction.

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12
Q

The chronic condition that can cause retrograde ejaculation is _

A

Diabetes.

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13
Q

Menopause - biologic changes

A
  1. Decline in blood levels of estrogen.
  2. Vaginal pH becomes more acidic.
  3. Subcutaneous fat and collagen decrease.
  4. Production of testosterone - the hormone of desire - declines.
  5. Changes in the sexual response cycle (neural).
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14
Q

Andropause - biologic changes

A
  1. Testosterone production declines 1-2% after age 30, but this is highly variable.
  2. Seminiferous tubules of testes - narrowed lumen, eventually to the point of obliteration of some tubules; diminished production of viable sperm.
  3. Seminal vesicles and prostate gland - secretions diminish, firm masses form around prostate urethra.
  4. Penis - venous and arterial sclerosis and fibroelastosis of corpus spongiosum.
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15
Q

Changes occurring within 1 year of menopause (in the absence of hormone therapy)

A
  1. Cervix, uterus, and fallopian tubes atrophy.
  2. The vaginal wall and mucosa become thinner - increasing the likelihood of UTIs.
  3. Vagina becomes shorter and narrower.
  4. Bartholin’s glands atrophy and secrete less fluid - causing the skin to become dry and more prone to injury.
  5. Less vaginal lubrication during excitement.
  6. The labia lose fullness and the amount pubic hair diminishes.
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16
Q

Changes occurring within 1-2 years of menopause

A
  1. The vulva and external genitalia shrink.

2. Introital stenosis - narrowed opening of the vagina.

17
Q

Because estrogen is stored in _ tissue, obese women may be less likely to experience atrophy of the vaginal epithelium after menopause.

A

Adipose.

18
Q

Estrogen replacement therapy is indicated for _

A
  1. Osteoporosis.
  2. Vasomotor symptoms.
  3. Genital atrophy.
19
Q

Androgens, including testosterone, are made by the _ and the _

A
  1. Adrenal glands.
  2. Ovaries.
    (So if a woman has an oophorectomy, she will still have testosterone production by the adrenals.)
20
Q

Functions of testosterone

A
  1. Sexual desire.
  2. Maintenance of muscle mass.
  3. Maintenance of bone mineral density.
21
Q

4 phases of the sexual response cycle

A
  1. Excitement phase.
  2. Plateau phase.
  3. Orgasm.
  4. Resolution phase.
22
Q

Sexual response cycle by gender

A
  1. Men= 3 minutes from desire to orgasm.
  2. Women= 12.5 minutes from desire to orgasm.
  3. Both genders= Plateau phase to orgasm is only 1 minute, therefore foreplay is important to balance out the experience.
23
Q

Some degree of erectile dysfunction is experienced by _ of men over the age of 70.

A

70%

24
Q

PLISSIT model

A
Tool to assess and develop interventions for *intimacy and sexuality issues*:
P = Permission
LI = Limited Information
SS = Specific Suggestions
IT = Intensive Therapies
25
Q

Erectile dysfunction medications should not be taken with _

A

Nitrovasodilators (e.g., nitroglycerin, amyl nitrate).

26
Q

_ is the only FDA-approved medication for increasing sexual stimulation in women.

A

Flibanserin (Addyi).

27
Q

Flibanserin (Addyi) contains a black box warning regarding _

A

A dangerous drop in blood pressure and possible fainting when taken with alcohol or anti-fungal medications.

28
Q

Older adults are at increased risk for contracting HIV due to _

A

Vaginal/epithelial changes paired with immune system changes, especially when sex is unprotected.

29
Q

Diminished _ affects sexual function in older adult women in several ways.

A

Estrogen production.