Lecture 8 - Chemical Hazards Flashcards
what are CAS registry numbers?
(CAS RNs or CAS #S)
unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures, alloys
what are the legislations apply for chemicals
-Safety health and welfare at work Act 2005 and associated regulations
-EU Regulation CLP 2008 and REACH 2007
What does GHS stand for
Globally Harmonized System
-classification and labelling of chemicals
What is a “Hazardous “ chemical under CLP 2008?
Physical Hazards (16)
◦ include flammables, explosives, oxidisers and
compressed gases
Toxicological Hazards (10)
◦ include toxic, carcinogenic, mutagenic, harmful, irritant, corrosive toxic for reproduction and sensitising
Environmental Hazards (4)
◦ Aquatic
◦ Ozone layer
◦ PBT/vPvB and POPs
Name hazardous chemicals that dont have a label
-Carbon monoxide
- Hydrogen sulphide
- Carbon dioxide
- Diesel fume
- Respirable silica dust (quartz fraction)
- Asbestos
What is flash point
the flammability of liquids
what are the components of the fire triangle
oxygen
fuel
ignition
what are the routes for hazardous exposure
-inhalation
-absorption
-ingestion
-trans placental
what is LD50
the amount of the chemicals that has a lethal effect on 50% of the target species
what can skin sensitisation also be known as?
allergic contact dermatitis
Name 2 examples of skin sensitisation
-nickel
-cadmium
what is carcinogens
substance that increases the likelihood of introducing a maligant tumor in man following a reasonabkle exposure
what is mutagens
substance that may affect the genetic system of the exposed person. It may cause heredity changed in the chromosome
what is toxic to reproduction
substances which if inhaled, ingested or penetrate the skin may
-produce/increase the incidence of non-inheritable adverse effects in the progeny
-impair male/female reproductive functions or capacity
what are teratogens
substance which interferes with the normal development of the foetus without inducing damage to the mother or killing foetus.
