Lecture 8

Question 1

Where does amplification occur

Answer 1

Step 3 ; one hormone/receptor complex can cause ma ny mRNA to be formed

Step 5: many proteins are formed from each mRNA

Question 2

Hydrophilic messengers

Answer 2

Several G- proteins associated with each receptor

Signalling systems can also include: channel - linked receptors (neurotransmitters), and other second hand messengers (ca2+, cGMP)

Question 3

Signal amplification Hydrophilic messengers

Answer 3

With 1 messenger benign to a receptor you can end with millions of proteins being made

Phenomenal amplification, also drives home another point… need to turn a signal OFF