Lecture 8 Flashcards
measures differences in the molar absorption of left-handed vs right-handed circularly polarized light
circular dichromism (CD) spectroscopy
Tertiary structures are stabilized by _____
non-covalent interactions between amino acid R groups; largely hydrophobic effect and polar interactions, can be stabilized by disulfide bonds
Contain several types of secondary structures; tend to be enzymes and regulatory proteins
Globular protein
Largely single type of secondary structure; provide support, shape, and protection
fibrous proteins
Fibrous proteins are _____ due to high concentrations of hydrophobic residues
H2O insoluble
Two _____ helices wrap about each other to form a left-handed supertwisted coiled coil
alpha-keratin
protein found in connective tissue; left-handed helix; three helices supertwist to form a right-handed triple helix
collagen
4 types of amino acids found in collagen are…
Gly, Ala, Pro, 4-Hyp
Keratin is rich in which residues?
Hydrophobic residues: Ala, Val, Leu, Ile, Met, Phe
Main protein in silk; formed by antiparallel beta-sheets
Fibroin
Fibroin is mainly composed of which residues?
Ala and Gly
Composed of different motifs folded together
Globular proteins
part of a polypeptide chain that is independently stable or could undergo movements as a single entity
domain
Combination of two or more tertiary units
Quaternary structure
multisubunit protein
oligomer
