Lecture 7- Eyelids Part 2 Flashcards
Most common form of blepharitis
squamous - non purulent - with increased marginal hyperemia and telangectasia- squamous types have a hypersensitivity component - pollutants, makeup, soaps etc
Most common bacteria in and around the eyes
Stachylococcus - gram + noncapsulated spheroidal bacteria - always on lid margin
Most common strains associated with eye conditions - strains of the most common bacteria on lids
Staph. Aureus and Staph. Epidermidis
Staph is the leading cause of marginal infiltrative keratitis, BUT what bacteria are more aggressive, more frequent proliferation, and cause more inflammatory reaction?
Streptococcus - and other gram positive bacterium
Toxin produced by staphylococcus aureus that causes a dermonecrosis, irritates occular surface - stimulating immune- inflammatory response
Alpha- Toxin
hyperacute forms of blepharitis with heavy discharge and preseptal cellulitis (for example) are caused by which bacteria
Streptococcus - G+, and some G-
condition caused by infection of eyelid margin- lash follicles and MG’s, become edematous and erythematous-greasy scales, lashes become crusted with dried serous fluid, typically caused by s. Aureus/epidermidis, or HSV/VZV, rapid onset/short duration, prevalent in warmer climates, affects middle aged females, related hordeolum/chalzion/SPK, cause preseptal cellulitis
Acute Marginal Blepharitis
condition involving poor hygeine and yellow pustules and gold crusts, could be mistaken for Acute Marginal Blepharitis, so you need to look for vesicles on the skin.
Impetigo
How to treat Acute Marginal Blepharitis
what happens if you remove the crusts?
lid hygiene 2-8 weeks BID to QID- hot compress, lid scrubs, baby shampoo diluted w water, Tea tree oil or cetaphil, Blephex, artifical tears for dry eye, antibiotics
What antibiotics should be employed for treatment of Actute Marginal Blepharitis?
Ointments - Bacitracin and EEM - staph Aureus/epidermidis
Lid scrubs with Gentamycin and tobramycin - aminoglycosides
Sulfonamides but 70% of staph not affected
Broad spectrum- Azythromycin - not as effective, no effect on MRSA
Trimethoprim.polyminB are effective
AB/steroid combo like genta/dexa, Tobradex, zylet,
AB with dual action anti-inflammatory, with Durasite vehicle, 1 drop bid x 2 days, then 1 drop 2-4 weeks, use for bacterial conjunctivitis
Azasite - topical medication for Acute Marginal Blepharitis
If a patient used Azasite for 4 week and is not seeing any improvement, start systemic antibiotics for MRSA and other infections. Which ABs could be used?
Doxycycline - 100 mg bid for 7-10 days (other strengths and duration for other conditions)
EES - 400 mg 4/day for 1-4 weeks
NO TETRACYCLINE OR DOXCICLINE in pregnant/nursing or kids under 8, Erythromycin 200 mg BID can be used instead
T or F: meibomian glands become clogged in posterior blepharitis only if there is rosacea present?
FALSE : Meibomian glands get clogged in posterior blepharitis, whether rosacea is present or not!
Condition marked by posterior lid margin redness, often seen in patients with MGD, indicated by crusting on anterior lashes, can lead to chrnoc conjunctivitis, madarosis, and tylosis- thickened lid margin, Treated with hygiene and ABs
Mixed Blepharitis- “mixed” often indicated by crusting on anterior lashes, Blepharitis MIXED with MGD
What is the difference between and External and Internal Hordeolum in terms of location and appearance, and which more often causes preseptal cellulitis
External Hordeolum: Zeis and Moll glands, with Head
Internal Hordeolum: Meibomian glands, no Head, more often preseptal cellulitis