Lecture 7 Flashcards
Deterministic effects occur above?
0.2Gy and higher
Factors of stochastic effects?
Dose
Number of affected cells
Sensitivity
Dose response relationship for stochastic effects
Unclear unlike deterministic effects
Epidemiological studies can provide statistical associations
Cancer risks with low doses of ionising radiation ?
Is not very clear
LNT curve
Straight
Downwardly decreasing slope?
indicates small number of hypersensitive individuals
Primary radiation dose
Bystander effects
Upward curving slope
Good description for induction of Leukaemia and chromosome aberrations
Threshold curve
Indicates a threshold for induction of sarcomas
Hormetic relationships
Favourable response to low doses of radiation exposure (hormesis)
Doubts about validity of LNT model/
-Cells are not affected by accumulating lesions
-Doses below 10mSv are eliminated by death
Doses slightly higher result in misrepair or irreversible lesions
Total risk of exposure to IR (population)
500 per million of general population exposed to 10mSV
Total risk of exposure to IR (radiation workers)
400 per million exposed to 10mSv