Lecture 7 Flashcards
Genetics of Viruses and Bacteria
What are pathogens
Bacteria and Viruses
Agents that cause disease symptoms in thier hosts
What are the 4 general properties of viruses
- A virus is a small nonliving particle with a nucleic acid genome
- Viruses are non-living; must be taken up by a living cell to replicate
- Tobacco mosaic virus (TMV) first virus discovered - can be spread by spraying the sap from an infeated plant onto another plant
- In 1900 the first human virus was identified - virus that causes yellow fever
What are viruses
Small infectious particle that consists of nucleic acid enclosed in a protein coat
Over 4000 different types
Vary greatly in their characteristics, including their host range, structure, and genome composition
What is a host cell
Cell that is infected by a virus
What is the host range
The number of species and cell types that can be infected
Can be narrow (few species) or broad (many species)
What are some of the notable structural differences
They range in size from 20 to 400 nm in diameter
All viruses have a capside (protein coat) but it varies in shape and complexity
Some have a viral envelop derived from host cell plasma membrane
Many virsus have protein fibers with a knob or spike glycoproteins that help them bind a host cell
What is bacteriophages
Viruses that infect bacteria; may have more complex protein coats
What are the 5 differences in genomes
- DNA or RNA
- Single stranded (ss) versus double stranded (ds)
- Linear versus circular
- Some viruses have more than one copy of the genome
- Vary considerably in size from a few thousand to more than 100 thousand nucleotides in length