Lecture 6 Trypanosome cruzi Flashcards
1
Q
Where is Trypanosoma cruzi located?
A
In central and South America
2
Q
The 4 main life stages of the parasites are
A
-Trypomastigotes
-Amastigotes
-Epimastigotes
-Metacyclics
3
Q
Mechanisms of Host Cell invasion
A
1.Exocytosis
2. Endocytosis
3. Autophagy -> lysosome targeting
4
Q
Methods available for chagas disease diagnosis
A
Parasitological Methods
-strout
-optical microscopy
-microhematocrit
Serological Methods
-ELISA
-indirect hemagglutination
-indirect immunoflourescence
Molecular Methods
-Obtaining DNA
-PCR
-qPCR
