Lecture 6: Cranial Nerves Flashcards

1
Q

What is the general organisation of CN nuclei in the brainstem?

A

Sensory nuclei lie lateral and motor nuclei lie more medial.

The most medial is somatic motor with parasympathetic motor beside them and head and neck motor below. Laterally to this is the visceral sensory, somatic sensory and special sensory nuclei. There are about 17 types of nuclei. They are located in the Tegmentum of the brainstem.

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2
Q

Which cranial nerves are purely efferent, afferent or mixed?

A

Efferent (motor) (5):

  • Trochlear Nerve
  • Abducens Nerve
  • Spinal Accessory
  • Hypoglossal
  • Occulomotor Nerve

Afferent (sensory) (3):

  • Optic Nerve
  • Olfactory Nerve
  • Vestibulocochlear

Mixed ():

  • Facial Nerve
  • Trigeminal
  • Glossopharyngeal
  • Vagus
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3
Q

For cranial Nerve I and II:

(a) Location
(b) Exit foramina
(c) Function
(d) Test

A

CN I - Olfactory Nerve

(a) Nasal Epithelium
(b) Cribriform Plate
(c) Special sensory - olfaction
(d) Change in sense of smell

CN II - Optic Nerve

(a) Emerging from the retina
(b) Optic canals
(c) Special Sensory - Vision
(d) Various vision Test such as Snellen’s Test, Fundoscopy, Colour vision etc.

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4
Q

Which sensory modality does not go through the thalamus?

A

Olfaction

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5
Q

For cranial Nerve III, IV and VI:

(a) Location
(b) Exit foramina
(c) Function
(d) Test

A

CN III Occulomtor Nerve

(a) Pontomesencephilic junction
(b) Superior orbital fissure
(c) Somatic motor - 4 extra ocular muscles and visceral motor (parasympathetic) - cillary and papillae muscles
(d) H Test

CN IV Trochlear

(a) Dorsal midbrain
(b) Superior orbital fissure
(c) Somatic motor - Superior oblique muscle
(d) H Test

CN VI Abducens

(a) Pontomedullary junction
(b) Superior orbital fissure
(c) Somatic motor - Lateral rectus
(d) H Test

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6
Q

Along which axes can the eye move?

A

The eyeball can move in 3 different axis - vertical axis through the eyeball, horizontal axis through the eyeball and an anterior-posterior axis. Adduction and abduction of the eyeballs refers to movement along the horizontal plane. Elevation and depression is along the vertical axis. Medial and lateral rotation is movement along the anterior-posterior axis. The top of the eyeball either intort or extorts. Muscles also do not act in isolation.

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7
Q

What muscles are used to:

  • Close the eye lid?
  • Open the eyelid?
A

Close the eyelid: Orbicularis oculi (CN VII)

Open the eyelid:

  • Levator palpebrae superioris (CN III)
  • Superior tarsal muscle - keeps the eyelid open (sympathetic)
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8
Q

What muscles are used to dilate and constrict the pupil and lens? What are these muscles innervated by?

A

Dilate the pupil - Dilators of the iris (sympathetic)

Constrict the pupil - 
Sphincter pupillae (CN III parasympathetic)
Change the lens shape:
Cillary muscles (CN III parasympathetic)
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9
Q

For cranial Nerve V:

(a) Location
(b) Exit foramina
(c) Function
(d) Test

A
CN V - Trigeminal Nerve 
V1 - Olfactory Branch 
(a) Pons 
(b) Superior orbital fissure 
(c) Somatic sensory to the upper face around the eyes 
(d) Test sensation around the area 

V2 - Maxillary Branch

(a) Pons
(b) Foreman Rotandum
(c) Somatic sensory to the middle of the face between the eyes and mouth
(d) Test sensation around the area

V3 - Mandibular Branch

(a) Pons
(b) Foramen Ovale
(c) Somatic sensory to the lower face around the mandible. Also branchial motor supply to the muscles of mastication, anterior belly of the digastric, tensor tympani etc.
(d) Test sensation around the area. To test motor component as the patient to protrude their jaw and move it side to side against resistance (ptypergoids).

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10
Q

Which 4 autonomic ganglia are associated with CN V?

A
  1. Cillary ganglia
  2. Pterygopalatine
  3. Submandibular
  4. Otic
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11
Q

For cranial Nerve VII and VIII:

(a) Location
(b) Exit foramina
(c) Function
(d) Test

A

CN VII - Facial Nerve
(a) Cerebellopoutine angle
(b) Internal acoustic meatus (entry) Stylomastoid foramen (exist)
(c) Somatic sensory - skin of the ear
Visceral motor - glands except the parotid
Special sensory - taste to the anterior 2/3rds of the tongue
Branchial motor - muscles of facial expression, stapedius and posterior belly of the digastric
(d) facial movements, taste and salivation

CN VIII -Vestibulococcular

(a) Cerebellopoutine angle
(b) Internal acoustic meatus
(c) Special sensory - hearing
(d) beside hearing tests

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12
Q

Give examples of branches CN VII gives off before existing the skull.

A

On its path before it exists the skull, it gives rise to many branches such as the greater petrosal branch of VII which innervates some of the glands causing secretion. It also gives rise to the branch to the chorda tympani. The terminal branches continue and exist through the stylomastoid foreman.

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13
Q

For cranial Nerve IX and X:

(a) Location
(b) Exit foramina
(c) Function
(d) Test

A

CN IX - Glossopharyngeal
(a) Posterolateral sulcus of the medulla (lateral to the olives)
(b) Jugular Foreamen
(c) Branchial motor - supplies muscles of the pharynx for swallowing
Visceral motor - parotid gland
Special sensory - taste to the posterior 1/3rd of the tongue
Somatic sensation - middle ear, pharynx and posterior tongue
Visceral sensory - carotid body and carotid sinus
(d) gag reflex

CN X - Vagus Nerve
(a) Posterolateral sulcus of the medulla
(b) Jugular foramen
(c) Branchial motor - larynx, uvula and pharynx
Visceral motor and Visceral sensory - GI and thorax
Special sensory - taste to the epiglottis and palette
Somatic sensation - epiglottis, skin of the external ear and larynx
(d) Test with speech and looking for any deviation of the uvula.

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14
Q

For cranial Nerve XI and XII:

(a) Location
(b) Exit foramina
(c) Function
(d) Test

A

CN XI - Spinal Accessory Nerve

(a) Posterolateral sulcus of the medulla, caudal medulla and rostral spinal cord
(b) Jugular foreamen
(c) Somatic motor to the sternocleidomastoid muscle and trapezius
(d) Shrugging the shoulders and rotating the head against resistance.

CN XII - Hypoglossal Nerve

(a) Anterolateral sulcus of the medulla
(b) Hypoglossal canal
(c) Somatic motor to the tongue
(d) Ask the patient to protrude their tongue and see if it is deviated

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15
Q

If the right CN XII is damaged which side will the tongue deviate to?

A

The right:

		If the CN XII is functioning on both sides the two muscles should contract simultaneously and the tongue should protrude straight. If there is an injury to the hypoglossal nerve, it will deviate to the side of the lesion as the muscle on the correct side will take over.
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16
Q

What is the innervation to the tongue?

A
  • Taste to the anterior 2/3rds of the tongue is by the facial nerve
  • Taste to the Posterior 1/3rds of the tongue is by the Glossopharyngeal Nerve
  • Taste to the epiglottis is by the Vagus
  • Somatic sensation to the epiglottis is by the Vagus
  • Somatic sensation to the posterior 1/3rd of the tongue - Glossopharyngeal
  • Somatic Sensation to the anterior 2/3rd of the tongue - Lingual Nerve (branch of V3)
  • Motor fibres - Hypoglossal Nerve
17
Q

Explain the interaction with autonomic fibres and the cranial nerves.

A

CN X: Does not give rise to a great deal of autonomic fibres in the head. Most go down the thoracic and abdominal viscera.

CN III: gives rise presynaptic fibres that pas towards the ciliary ganglion. From here they synapse with post synaptic fibres and pass to the sphincter pupillae of the eye and allow constriction of the pupil. They do this via CN V1.

CN VII: Contains presynaptic fibres that synapse in the pterygopalatine ganglion and some in the submandibular ganglion. Form the pterygopalatine gland that pass towards the lacrimal gland via V2.
From the submandibular ganglion they travel to the submandibular and sublingual gland via V3.

CN IX - presynaptic fibres go to the otic ganglion. Postsynaptic ganglion from the otic gland go to the parotid gland via V3.

18
Q

How does sympathetic input from the cranial nerves get to the target organs in the head?

A

Sympathetic input come from the superior cervical ganglion (upper limit of the sympathetic chain), post synaptic fibres an lead towards the common carotid. As the common carotid artery branches it receives branches from the superior cervical branches. These run up through the arteries and innervate the various target organs to the head.