Lecture 5.1 - GI Flashcards
What kind of TPN is better for patients on fluid restrictions?
Those with higher percentages (10-30%) of fat emulsion provide large numbers of calories in relatively small amounts of fluid.
Note that fat emulsions are contraindicated in patients with hyperlipidemia.
What are the two kind of parenteral nutrition administration?
Peripheral and Central
–> PPN contains fewer nutrients and is less hypertonic (800mmol/L). Still poses risk for phlebitis or fluid overload.
What is refeeding syndrome?
Fluid retention and low phosphate, Mg, K.
Can occur any time a malnourished pt starts aggressive nutritional support.
What is Barrett’s esophagus?
When the normal squamous epithelium of the esophagus becomes replaced with columnar epithelium from the stomach.
Associated with repeated episodes of GERD.
What are the clinical manifestations of GERD?
Hx of heartburn, regurgitation, dyspnea or coughing.
What are some complications of GERD?
–> Esophagitis
–>Barrett’s esophagus.
Repeated esophagitis might lead to…
Scar tissue formation (esophageal stricture) that may result in dysphagia.
What is the purpose of diagnostic studied for GERD? What diagnostic studied are used?
TO determine the cause, such a a hiatal hernia.
–> Barium swallow
–> Endoscopy
–> Biopsy
–> pH tests
How can GERD be managed?
Lifestyle modifications
–> Avoid diet and medication factors that exacerbate (high fat, milk, spicy). High protein, low fat.
–> Avoid meals before bed.
–> Avoid smoking
Medication:
–> PPI, H2-blockers, antacids
What is the difference between a sliding and rolling esophageal hernia?
A sliding hernia involves the stomach sliding partially above the diaphragm into the thoracic cavity
A rolling hernia involves the esophagogastric junction remaining in normal position, but fundus rolls up through diaphragm forming a pocket beside the esophagus.
What is achalasia?
Absence of peristalsis in the lower 2/3rds of the esophagus.
What is gastritis?
Inflammation of the gastric mucosa
May be:
–> Acute/Chronic
–> Diffuse/Localized
Which medications can cause gastritis?
ASA, corticosteroids, NSAIDs
Which dietary factors can cause gastritis?
Alcohol and spicy food
Which microorganisms can cause gastritis?
–> H. pylori (Acquired in Childhood)
–> Species of salmonella
–> Species of staphylococcus
What are the three subtypes of gastritis?
1 - autoimmune (body and fundus)
2 - Diffuse antral (Antrum)
3 - Multifocal (diffuse throughout)
Anorexia, N&V, epigastric tenderness, and a feeling of fullness are associated with what condition?
Acute gastritis.
Chronic gastritis has similar manifestations, but may also be accompanied with a loss of intrinsic factor –> B12 deficiency –> Pernicious anemia
What stomach condition should you be aware of in those with chronic alcoholism?
Hemorrhage is commonly associated
Chronic gastritis –> B12 deficiency
What diagnostic studies are used to diagnose acute gastritis?
–> Hx of drugs and alcohol
–> Endoscopy w biopsy for definitive diagnosis
Breath, urine, serum (gold standard), stool and biopsy tests are available to test for H. Pylori.
–> CBC for anemia (B12/hemorrhage)
–> Stools for occult blood
How is acute gastritis managed?
Eliminating cause and preventing future exacerbation is main goal
Plan of Care
–> bed rest
–> NPO
–> IV Fluids + antiemetics
For severe acute gastritis an NG tube may be placed to keep stomach empty and free from noxious stimuli. Check VS frequently or hemorrhage is considered likely.
How is chronic gastritis treated?
Focus is on evaluating and eliminating specific cause.
Plan of Care:
–> Antibiotics (if indicated)
–> Cobalamin if necessary. Discussion about future supplementation
Future plan:
–> six small meals a day followed by antacid
–> Smoking cessation
–> Monitor Ca if taking calcium rich antacids
What is Zofran?
Ondansetron
–>5-HT blocker (antiemetic)
What should you be aware of for patients with excessive vomiting?
HypoK
What is gravol?
Dimenhydrinate
–>Antihistamine for &V