Lecture 5 LOs Flashcards
Describe the components of the lymphatic system
-Organized lymph tissue-spleen-location?
- Located between ribs 9, 10, and 11th ribs on the left side
- Between left hemi-diaphragm and peritoneal cavity
Describe the components of the lymphatic system
-Organized lymph tissue-spleen-movement of the diaphragm is important for?
Movement of the diaphragm is important for the homeostatic movement of splenic fluids
Describe the components of the lymphatic system
-Organized lymph tissue-spleen-Functions?
- Destroys deformed/damaged RBCs
- Synthesizes immunoglobulins
- Clearance site for:
- Antigens, microorganisms, and poorly organized bacteria
Describe the components of the lymphatic system
-Organized lymph tissue-liver?
- Half of the body’s lymph is formed here
- Pressure sensitive organ
- Affected by the muscular action of the thoraco-abdominal diaphragm
- The liver is the “gate-keeper” of the shared hepato-biliary-pancreatic venous and lymphatic region
- Also clears bacteria
Describe the components of the lymphatic system
-Organized lymph tissue-thymus-location?
- Located in the superior mediastinum
- Anterior to great vessels
- Extends into the neck
Describe the components of the lymphatic system
-Organized lymph tissue-thymus-when is it largest?
- Largest in infants (age 2)
- After puberty-involutes
- Adults-replaced by fatty tissue
Describe the components of the lymphatic system
-Organized lymph tissue-thymus-function?
- Provide cells involved in maturation of immune system
- Processing site T cells
- Little or no function in adult
Describe the components of the lymphatic system
-Organized lymph tissue-tonsils?
- Multiple areas in ring formation in posterior oropharynx
- Palatine-lateral pharynx
- Lingual-posterior 1/3rd of tongue
- Pharyngeal-adenoids at nasopharyngeal border
Describe the components of the lymphatic system
-Organized lymph tissue-tonsils-function?
- Provide cells to influence and build immunity early in life
- Non-essential to adult immune function
Describe the components of the lymphatic system
-Organized lymph tissue-appendix?
- Located at the medial surface of the cecum
- Exact function unknown
- Presume it offers support to immune system
Describe the components of the lymphatic system
- Organized lymph tissue-Visceral lymphoid tissue-GI:
- 2 components?
- Location of each component?
- Peyer’s patches-distal ilium
- Lacteals-lymphatic capillaries in each villi in small bowel
- Fats enter circulation via GI system
Describe the components of the lymphatic system
-Organized lymph tissue-Visceral lymphoid tissue-pulmonary-function?
-Aids filtration of toxins from lungs
Describe the components of the lymphatic system
-Organized lymph tissue-Lymph nodes?
- MOST HIGHLY ORGANIZED LYMPH TISSUE
- Dispersed along the course of lymph vessels
- Primary purpose is for filtration of lymph
Describe the components of the lymphatic system
-Organized lymph tissue-Lymph nodes-Two types?
- Superficial
- Deep
Describe the components of the lymphatic system
- Organized lymph tissue-Lymph nodes-superficial-location?
- Receive?
- Follows subcutaneously with superficial veins
- Receive (lymph?) from skin/deep tissues off upper and lower extremities/head and neck
Describe the components of the lymphatic system
-Organized lymph tissue-Lymph nodes-superficial-drain into 3 main groups of nodes (from extremities into the core)?
- Cervical
- Axillary
- Inguinal
Describe the components of the lymphatic system
-Organized lymph tissue-Lymph nodes-superficial-cervical drains?
head/supraclavicular and upper extremity extremity drain to jugular nodes
Describe the components of the lymphatic system
-Organized lymph tissue-Lymph nodes-superficial-axillary drains?
Infraclavicular to umbilicus, drain to axillary nodes and then to subclavian
Describe the components of the lymphatic system
-Organized lymph tissue-Lymph nodes-superficial-inguinal drains?
Caudal to umbilicus drain to inguinal nodes and then lumbar
Superficial LNs in head/neck?
Submental, Virchow’s
Superficial LNs in abdomen?
Cisterna chyli, celiac
Superficial LNs in upper extremity?
Deltopectoral, axillary, cubital
Superficial LNs in lower extremity?
superficial inguinal, popliteal
Deep LNs-general location?
Beneath fascia and muscles, follows deep veins
Describe the components of the lymphatic system
-Lymph channels/collecting duct-Perfuses all tissues of the body except?
- CNS (although new research indicates it does have lymph vessels)
- Epidermis (includes hair and nails)
- Endomysium of muscles and cartilage
- Bone marrow
- Selected portions off peripheral nerves
- Exceptions still possess direct diffusion
Lymph channels/collecting duct
-Where do they run?
They follow the course of deep and superficial veins
Describe the components of the lymphatic system
-Lymph fluid?
-Substance that leaks out of arterial capillaries, into the interstitium and into single-cell lymphatic vessels
Describe the components of the lymphatic system
-Lymph fluid components?
-Proteins, salts, fats, lymphocytes (primary cell), clotting factors, large particles (bacteria, viruses)
Structure of the lymphatic system?
- Unidirectional fluid flow in channels
- Flow controlled by one-way valves
- Channels/nodes surround major organs and vasculature
- Unite with thoracic duct or right lymphatic duct