lecture 5 Flashcards
1
Q
Alpha-BSM applications?
A
Dental Applications & Orthopedic
2
Q
controls drug release in ocusert?
A
EVA: Ethylene-vinyl acetate
3
Q
drugs used in the gastro-retentive system?
A
- Drugs with limited acid solubility: Phenytoin
- Drugs that suffer instability in gastric environment erythromycin
- Drugs intended for selective release in colon: 5-Amino-Salycilic Acid
4
Q
factors that affect gastric retention?
A
- density of dosage form
- shape & size of dosage form
- food intake & its nature
- Gender & Age
5
Q
Mechanism of MucoAdhesion?
A
- Wetting theory
- Diffusion theory
- Chemical Bond formation: Primary (Covalent)& Secondary (Van der waals & hydrogen bond)
6
Q
Mucoadhesion characteristics?
A
- flexibility
- hydrophilicity
- hydrogen bonding
- high mwt
- low surface tension