Lecture 4: Tyrosine Kinase Receptors Flashcards
1
Q
What are tyrosine kinase receptors?
A
Receptor tyrosine kinases (RTKs) are membrane glycoproteins that regulate many cellular processes (cell migration, organ development, cell proliferation, and differentiation).
2
Q
How many human RTKs are there?
How many subfamilies are there?
A
There are 58 human RTKs, these are divided into 20 subfamilies.
3
Q
Give one example of a common RTK
A
The epidermal growth factor receptor is a member of the erbB family of receptors (subtype of RTKs).