Lecture 4 Skeletal Muscle and Nerve tissue Flashcards

1
Q

Muscle cell

A

Made up of myofibrils

Myofiber/Myocyte/Muscle fiber

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2
Q

Fascicle

A

group of myofibers

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3
Q

Muscle

A

group of fascicles

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4
Q

nebulin

A

“ruler” for determining

length of actin filament

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5
Q

M-line:

A

attachment site for myosin

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6
Q

Z-disk:

A

separates sarcomeres; attachment site for actin and titin

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7
Q

H band:

A

space on either side of M-line where there is no actin

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8
Q

A band:

A
distance from the end of one myosin head to the head of the
opposite myosin (overlap of actin + myosin and H band)
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9
Q

I band:

A

space on either side of the Z-disk where there is no myosin

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10
Q

Sliding Filament Mechanism

A
Thin filaments slide past
thick filaments
• This brings Z-disk’s closer
together
• All myofibrils in a muscle
contract at the same time
making the entire muscle
shorten
• *Actin and myosin DO NOT
change in length, they
simply overlap each other
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11
Q

Sarcolemma:

A

membrane around

each muscle cell

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12
Q

Transverse (T) tubules:

A

membrane
system penetrating the muscle cell
to convey electrical impulses from
sarcolemma into cell

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13
Q

Sarcoplasm:

A

cytoplasm of muscle

cell

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14
Q

Sarcoplasmic Reticulum:

A

tubular

system acting like the smooth-ER

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15
Q

Terminal Cisternae =

A

flattened sac of
SR on either side of a Transverse T
Tubule
-store Ca2+

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16
Q

Triad

A

T tubule + 2 Terminal

cisternae (1 on either side)

17
Q

End Feet:

A

connect T tubules with

SR to allow Ca release

18
Q

Neuromuscular Junction (NMJ)

A
Skeletal muscle
innervated by peripheral
a-motor neurons from
the anterior horn of the
spinal cord
19
Q

Neuromuscular Spindle Apparatus Action

A

reflexive response to
prevent overstretching of a
muscle

20
Q

Extrafusal muscle fibers:

A

contract

the muscle

21
Q

Intrafusal muscle fibers:

A

sense length

and rate of change of the muscle

22
Q

Type Ia sensory nerve fibers:

A

afferent innervation of intrafusal fibers

sense stretch and rate of change of intrafusal fibers

23
Q

a-motor nerve fibers:

A

efferent
innervation of extrafusal muscle fibers
-receive signal from type Ia fibers

24
Q

g-motor nerve fibers:

A

efferent
innervation of intrafusal muscle fibers
-receive signal from type Ia fibers

25
Q

soma/body

A

contains all organelles of neuron

26
Q

nissle substance

A

abundant RER w/in the cytoplasm of soma

27
Q

dendrite

A

receives signals from other neurons

28
Q

axon hillock

A

connection between soma and axon

29
Q

axon

A

conveys electrical impulse to synapse

30
Q

synapse

A

transfers electrical impulse from neuron to target tissue

31
Q

Multipolar:

A

multiple

dendrites and one axon

32
Q

Bipolar:

A

single dendrite
(multiple extensions) and
one axon

33
Q

Pseudounipolar:

A

one
cell process with a single
dendrite branch and axon
branch

34
Q

Schwann cell:

A

surround axon and create myelin sheath in PNS

– Wrap around one part of one axon

35
Q

Oligodendrocyte:

A

surround axon and create myelin sheath in CNS

– Wrap around a part of many axons

36
Q

Myelin Sheath:

A

circumferential layers of myelin allowing for faster

signal conduction velocity