Lecture 4- Principles of Biopsy

Question 1

Biopsy if lesion persists for more than …. with the no know etiology

Answer 1

2 weeks

Question 2

Biopsy for any inflammatory lesion that does not respond to local therapy within …

Answer 2

2 weeks

Question 3

Biopsy when there are … changes in epithelial tissue

Answer 3

persistent

Question 4

Biopsy when there are lesions that … with fxn

Answer 4

interfere

Question 5

Biopsy when there are bone lesions that are not identifiable by … and… findings

Answer 5

clinical and radioraphical

Question 6

4 types of biopsies

Answer 6

oral cytology
aspirational biopsy
incisional
excisional

Question 7

indications for cytology

Answer 7

large areas or mucosal change

need for monitoring dysplastic changes

Question 8

technique for cytology

Answer 8

moistened tongue depressor or cement spatula

scrape lesion

smear and fixate over glass slide

Question 9

indications for aspiration

Answer 9

lesions suspected to contain fluid

intraosseous lesions

Question 10

technique for aspiration

Answer 10

18 G needle, 5 or 10 ml syringe

repeated repositioning

cortical perforation if needed

Question 11

indications for incisional

Answer 11

extensive lesion >1cm

hazardous location

high suspicion of malignancy

closure

Question 12

technique for incisional

Answer 12

representative area

wedge fashion (deep and narrow)

include normal tissue

Question 13

indications for excisional

Answer 13

small lesion <1cm

benign appearance

closure

Question 14

technique for excisional

Answer 14

entire lesion

margin of tissue (2-3mm) or 5mm if malignant

Question 15

specimen should be put in a 10% …. solution (4% …)

and it should be placed in a volume 20X the specimen and totally immersed

Answer 15

10% formalin

4% formaldehyde

Question 16

to encourage hemostasis after a soft tissue biopsy, avoid …. suction and electrocautery

Answer 16

high volume

Question 17

5 general benign cases

Answer 17

squamous papilloma
hemangioma
fibroma
mucocele
dentigerous cyst