Lecture 4- Principles of Biopsy Flashcards
Biopsy if lesion persists for more than …. with the no know etiology
2 weeks
Biopsy for any inflammatory lesion that does not respond to local therapy within …
2 weeks
Biopsy when there are … changes in epithelial tissue
persistent
Biopsy when there are lesions that … with fxn
interfere
Biopsy when there are bone lesions that are not identifiable by … and… findings
clinical and radioraphical
4 types of biopsies
oral cytology
aspirational biopsy
incisional
excisional
indications for cytology
large areas or mucosal change
need for monitoring dysplastic changes
technique for cytology
moistened tongue depressor or cement spatula
scrape lesion
smear and fixate over glass slide
indications for aspiration
lesions suspected to contain fluid
intraosseous lesions
technique for aspiration
18 G needle, 5 or 10 ml syringe
repeated repositioning
cortical perforation if needed
indications for incisional
extensive lesion >1cm
hazardous location
high suspicion of malignancy
closure
technique for incisional
representative area
wedge fashion (deep and narrow)
include normal tissue
indications for excisional
small lesion <1cm
benign appearance
closure
technique for excisional
entire lesion
margin of tissue (2-3mm) or 5mm if malignant
specimen should be put in a 10% …. solution (4% …)
and it should be placed in a volume 20X the specimen and totally immersed
10% formalin
4% formaldehyde