Lecture 4 Clinical Perals Flashcards
2nd MC anemia?
ACD
ACD features?
- Usually mild
- Often co-exists with others
- Tx underlying prob
Multi-factorial anemias of micro and macro anemias combined will present as what type of anemia?
Normocytic anemia
Renal failure associated anemia is due to?
Slow reduction in EPO production
Types of anemia that cause pancytopenia?
Aplastic anemia - MC
Causes of aplastic anemia?
Fanconi’s
PNH
Hemolytic anemias are recognized by?
Reliable rapid hematocrit drop in the absence of bleeding
- Decreased haptoglobin,
- increased indirect bilirubin,
- increased LDH
- increased RC and RBI
Name some intrinsic defects?
HS
G6PD
Sickle cell
Name some extrinsic defects
AIHA warm/cold
+ Coombs test =?
AIHA
AIHA warm tx?
Immunosuppression
AIHA cold tx?
Avoid cold
What is microangiopathic hemolytic anemia (MAHA)?
Intravascular hemolysis and thus schistocytosis
Often forgotten causes of anemia?
Infection
- parvo
- s. Pneum
- plasmodium