Lecture 4 - Bioreactor Modelling Flashcards
1
Q
Draw a generalised bioreactor diagram including the key parameters
A
FiSi in Gi in C in gas phase VPXS in liquid phase FoSoXoPo out GoCo out
2
Q
Write down the key kinetic equations: Kinetics Biomass formation Substrate Formation Product Formation CO2 formation
A
u = umaxS/Ks + s rx = uX rs = uX/Yxs rp = uXYps/Yxs rc = UXYcs/Yxs
3
Q
5 assumptions for a generalised mass balance
A
- Perfect mixing
- Steady flows
- Negligible concentrations of product or substrate in gas phase
- Negligible concentrations of CO2 in the liquid phase and inlet gas stream
- No biomass in feed stream
4
Q
Write the generalised mass balances Substrate Biomass Product CO2
A
slide 7
5
Q
Convert the general equations to batch, fed batch and continuous reactors
A
slide 8-10
6
Q
What are the components of process control design (5)
A
- Define control objectives
- Select measured variables (primary or secondary)
- Select manipulated variable
- Identify relationship between measured and manipulated variables (modelling)
- Design a control algorithm
7
Q
Derive equations for the control of feed and substrate in fed batch and continuous reactors explain how you would use each equation
A
slide 13-19