Lecture 4 - Bioreactor Modelling Flashcards

1
Q

Draw a generalised bioreactor diagram including the key parameters

A
FiSi in
Gi in 
C in gas phase 
VPXS in liquid phase
FoSoXoPo out
GoCo out
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2
Q
Write down the key kinetic equations:
Kinetics
Biomass formation
Substrate Formation
Product Formation
CO2 formation
A
u = umaxS/Ks + s
rx = uX
rs = uX/Yxs
rp = uXYps/Yxs
rc = UXYcs/Yxs
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3
Q

5 assumptions for a generalised mass balance

A
  • Perfect mixing
  • Steady flows
  • Negligible concentrations of product or substrate in gas phase
  • Negligible concentrations of CO2 in the liquid phase and inlet gas stream
  • No biomass in feed stream
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4
Q
Write the generalised mass balances 
Substrate
Biomass
Product
CO2
A

slide 7

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5
Q

Convert the general equations to batch, fed batch and continuous reactors

A

slide 8-10

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6
Q

What are the components of process control design (5)

A
  • Define control objectives
  • Select measured variables (primary or secondary)
  • Select manipulated variable
  • Identify relationship between measured and manipulated variables (modelling)
  • Design a control algorithm
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7
Q

Derive equations for the control of feed and substrate in fed batch and continuous reactors explain how you would use each equation

A

slide 13-19

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