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Pharm 2 > Lecture 4 > Flashcards

Lecture 4 Flashcards

1
Q

Nitrous tank color

A

Blue

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2
Q

Nitrous tank color

A

Blue

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3
Q

O2 tank color

A

Green

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4
Q

Nitrous qualities

A

Inorganic, nonflammable, sweet-smelling gas

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5
Q

MAC definition

A

Conc at which half the pop will not respond to a skin incision

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6
Q

MAC of Nitrous

A

105%

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7
Q

Blood-Gas solubility

A

Proportion of the drug in your blood/circulation to in your lung

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8
Q

Blood/Gas Solubility of N2O

A

0.5 - so 1 part in blood to 2 parts in lungs- runs right through body
Very insoluble- N20 runs to other parts of body

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9
Q

N2O High Solubility effect on other drugs

A

Causes higher relative percentage of drug in alveoli and causes them to have higher effect

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10
Q

Pharmacodynamics of Nitrous

A

Analgesia
Frequently Anxiolytic
Blunts gagging reflex

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11
Q

What to do when ending N2O administration

A

3-5 min of 100% O2

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12
Q

Contraindications to N2O

A

Recent GI surgery w/ sutures

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13
Q

Cautions to N2O use

A

COPD or Emphysema
Pregnant First Trimester
Mental issues
Otitis Media

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14
Q

Symptoms of Chronic Exposure to Nitrous

A

Bone marrow depression, sensory depression in extremities

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15
Q

Oversedation by Nitrous Symptoms

A

Dysphoria- laughing, crying
Uncooperative
Incoherent
Spastic Movements- About to go unconscious!!

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16
Q

Appropriate level of ambient N2O

A
17
Q

If pt gets nauseated

A

Stop Nitrous and put on O2 and don’t move pt!

18
Q

Level of ambient N2O at which have problems

A

1000-5000 ppm

19
Q

Blood-Brain Saturation of Nitrous

A

3-5 min

20
Q

N2O vs N2

A

N2O is 37 times more soluble than N2–> enters closed spaces fast–> caution w/ Otitis Media, Emphysema, and gas-filled instestine w/ bowl obstruction

21
Q

Full tank of O2

A

2000 psi, 660L

22
Q

Full tank of N2O

A

750 psi, 1590L

23
Q

Volume N20 when all liquid used up and pressure finally starts to drop

A

400L

24
Q

Symptoms of Chronic Abuse of Nitrous

A

Central Nervous System myeloneuropathy, multiple sclerosis like symptoms, and hematological effects

25
Q

Chronic Exposure to N2O can cause

A

Bone marrow depression
Anemia due to inactivation of B12 and subsequent decreased methionine production
Decrease in fertility
Neurological disease

Pharm 2 (11 decks)

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