Lecture 4 Flashcards
Nitrous tank color
Blue
Nitrous tank color
Blue
O2 tank color
Green
Nitrous qualities
Inorganic, nonflammable, sweet-smelling gas
MAC definition
Conc at which half the pop will not respond to a skin incision
MAC of Nitrous
105%
Blood-Gas solubility
Proportion of the drug in your blood/circulation to in your lung
Blood/Gas Solubility of N2O
0.5 - so 1 part in blood to 2 parts in lungs- runs right through body
Very insoluble- N20 runs to other parts of body
N2O High Solubility effect on other drugs
Causes higher relative percentage of drug in alveoli and causes them to have higher effect
Pharmacodynamics of Nitrous
Analgesia
Frequently Anxiolytic
Blunts gagging reflex
What to do when ending N2O administration
3-5 min of 100% O2
Contraindications to N2O
Recent GI surgery w/ sutures
Cautions to N2O use
COPD or Emphysema
Pregnant First Trimester
Mental issues
Otitis Media
Symptoms of Chronic Exposure to Nitrous
Bone marrow depression, sensory depression in extremities
Oversedation by Nitrous Symptoms
Dysphoria- laughing, crying
Uncooperative
Incoherent
Spastic Movements- About to go unconscious!!
Appropriate level of ambient N2O
If pt gets nauseated
Stop Nitrous and put on O2 and don’t move pt!
Level of ambient N2O at which have problems
1000-5000 ppm
Blood-Brain Saturation of Nitrous
3-5 min
N2O vs N2
N2O is 37 times more soluble than N2–> enters closed spaces fast–> caution w/ Otitis Media, Emphysema, and gas-filled instestine w/ bowl obstruction
Full tank of O2
2000 psi, 660L
Full tank of N2O
750 psi, 1590L
Volume N20 when all liquid used up and pressure finally starts to drop
400L
Symptoms of Chronic Abuse of Nitrous
Central Nervous System myeloneuropathy, multiple sclerosis like symptoms, and hematological effects
Chronic Exposure to N2O can cause
Bone marrow depression
Anemia due to inactivation of B12 and subsequent decreased methionine production
Decrease in fertility
Neurological disease
