Lecture 3_Immuno Flashcards
What are features of innante immunity
- important in controlling anf eradicating infection before the adaptive immunity becomes active
- ready to go as soon as the body is breeched by infection
- 1st line of defense. Already in place and it is ready to goooo
- has NO zero nada memory
- helps provide information to the adaptive immune response (dendritic cells are the bridge-APC’s)
What time after infection will the innate immune system activate?
happens quick within the first 6-12 hrs
adaptive immunity takes about a week to kick in
OPSONIN
An opsonin is something that “coats” microorganism and in doing so, targets it for destruction by phagocytes
PAMPS
Pathogen Associated Molecular Patterns
What is the role of a PAMP?
Pathogen Associated Molecular Patterns
~ The innate immune system recognizes only a limited number of microbial products that are shared among broad groups of microbes
~Such molecules ARE NOT present on host cells, and are often structures of microbes that are essential for the survival and infectivity of microbes
, Influenza, Mumps, Parainfluenza and Measles all have a ……….PAMP
single stranded RNA (ssRNA) genome.