Lecture 34 - Tools for Reviewing the Medical Literature

Question 1

What is an NCT number and what is its purpose?

L34 S3

Answer 1

• unique number assigned to all studies prior to initiation
• assigned through clinicaltrials.gov

-purpose is to reduce publication bias, not publishing negative or unfavorable research

Question 2

What checklist is used for interventional studies?

L34 S12

Answer 2

-CONSORT (CONsolidated Standards Of Reporting Trials)

Question 3

What checklist is used for systematic reviews of interventional studies?

L34 S17

Answer 3

-PRISMA (Prefered Reporting Items for Systematic reviews and Meta-Analyses)

Question 4

What checklist is used for observational studies?

L34 S18

Answer 4

-STROBE (STrengthening the Reporting of OBservational studies in Epidemiology)

Question 5

What checklist is used for non-randomized studies?

L34 S21

Answer 5

-TREND (Transparent Reporting of Evaluations with Non-randomized Designs)

Question 6

What checklist is used for tumor marker prognostic studies?

L34 S22

Answer 6

-REMARK (REporting recommendations for tumor MARKer prognostic studies)

Question 7

What checklist is used for genetic risk prediction studies?

L34 S23

Answer 7

-GRIPS (Genetic RIsk Prediction Studies)

Question 8

What checklist is used for diagnostic studies?

L34 S24

Answer 8

-STARD (STAndards for the Reporting of Diagnostic accuracy studies)

Question 9

What checklist is used for systematic reviews of diagnostic studies?

L34 S25

Answer 9

-QUADUS-2 (QUality Assessment of studies of Diagnostic Accuracy in Systematic reviews)