Lecture Flashcards
Gross anatomy of the renal system
kidney, ureters, bladder, urethra
3 main functions of the urinary system
- removal of waste from body fluids
- elimination of waste into the environment
- homeostatic regulation of blood plasma
The medial side of the kidney where the vessels and nerves after and leave is referred to as the …
Hilum
What does the renal fascia do
Anchors the kidney to the abdominal wall
Outer layer of the kidney is called?
Renal cortex (shell)
Middle layer of the kidney is called the…
and contains cone shaped structures called…
Renal medulla
renal pyramids
What is the renal pelvis
a cone shaped collecting are that connects the ureters to the kidney
Minor calyx
drains urine from the renal medulla to the major calyx
Major calyx
drains urine from the minor calyx to the renal pelvis
How much of the cardiac output flows through the kidney every minute?
25%
The afferent artery enters the kidney and becomes what structure
The glomerulus (the main filter)
The efferent arteriole forms after leaving the glomerulus and becomes …
peritubular capillaries that permit reabsorption from the convoluted tubules
What is unique about the capillary beds in the kidney
No other organ in the body has 2 distinct capillary beds
What are the structural and functional units of the kidney and where are they found
The nephrons
In the cortex and medulla
Another name for the glomerulus capsule
Bowmans capsule
What is the path that they kidney filtrate takes from the bowman capsule to the collecting ducts
PCT - Loop of Henle - DCT
How many nephrons are contained in the kidney
1.25 million
What is the function of the podocytes
They wrap around the glomerular capillaries and form slits that permit filtrate to pass into the glomerular capsule, but are small enough to prevent larger molecules such as protein from leaving the blood stream
What is the glomerular filtration rate for a normal adult
125ml/min
What does the initial filtrate in the bowman capsule contain
glucose, salts, mineral, water and metabolic wastes
Where does initial reabsorption occur
PCT and deposited into surrounding interstitial fluid
As the interstitial fluid becomes more concentrated what happens next?
Water moves from the filtrate by osmosis into the interstitial fluid. The interstitial fluid then moves into the peritubular capillaries to restore homeostatic balance
What happens in the descending portion of the loop of henle?
It is permeable to water but impermeable to Na+ and Cl-
What is the permeability of the ascending loop of henle?
Permeable to Na+ and Cl- but impermeable to H20
After leaving the loop of henle and entering the DCT how much of the initial filtrate has been reabsorbed
85% of the water
80% of the solutes depending upon the bodies needs
What is the structure at site where the efferent arteriole and the DCT meet?
Juxtaglomerular apparatus
What do the pressure sensitive cells in the juxtaglomerular apparatus do?
release Renin in response to low BP
What are the macula dense cells sensitive to?
Sensitive to chemical changes and monitor the filtrate concentration in the DCT
What does Renin do?
converts plasma protein angiotensinogen into angiotensin I