Lecture 3: Schizophrenia Flashcards
0
Q
Anti-Psychotics
-Atypical -**Preferred / less side effects
A
- Abilify
- Zyprexa
- Resperidal
- Geodone
1
Q
Anti-Psychotics
-Traditional
A
- Haldol
- Thorizine
- Prolixin
- Navane
2
Q
Schizophrenia
-Positive Symptoms
A
- Hallucinations
- Delusions
- Exaggerations and distortions of normal perceptions and thinking
3
Q
Schizophrenia
-Negative Symptoms
A
- Inexpressive facial expressions
- Monotone monosyllabic speech
- Few gestures
- Lack of interest in the world and other people
- Inability to feel pleasure
- Absence of normal emotion and social sensitivity
4
Q
Mood Stabilizer
-Lithium
A
- When a patient is on lithium, ALWAYS get a blood lithium level
- Therapeutic range is 0.5-1.5
5
Q
Anticholinergics & Traditional Anti-Psychotics
A
- Traditional anti-psychotics block dopamine receptors
- Anticholinergics block acetylcholine
- Dopamine causes muscle to relax, Acetylcholine causes muscles to contract
6
Q
Anticholinergics
-Most Common Meds
A
- Cogentin (Benzatropine) Primary Med
- Benadryl (diphenhydramine)
- Artane (Trihexphyenidyl)
7
Q
Anti-psychotics
-Clazaril (Clozapine)
A
- Monitor WBC’s before admin
- Hold if immunocompromised - Go through national registry
- Requires trial of 3 meds before pt is placed on this med
8
Q
Anti-psychotics
-Clazaril (Clozapine)
Side Effects
A
- Severe Salivation
9
Q
Anti-Psychotics
-Side Effects
A
- Akathisia
- Tardive Dyskinesia
- Acute Dystonia
- Neuroleptic Malignant syndrome
10
Q
Anti-Psychotic Side Effects
-Akathisia
A
- Restless leg syndrome
- Involuntary movement of lower legs
- Manifests as urge to move the legs to stop unpleasant sensation
11
Q
Anti-Psychotic Side Effects
-Tardive Dyskinesia
A
- Permanent neurological disorder r/t taking longterm traditional antipsychotics
- Pt will have worm-like movement of the tongue
- facial twitching, lip smacking - Non reversable
12
Q
Anti-Psychotic Side Effects
-Acute Dystonia
A
- Sustained muscular spasms that are often painful producing twisting abnormal postures
- 1st thing you notice is muscle stiffness –tight shoulders
Treatment - IM Anticholinergic
13
Q
Anti-Psychotic Side Effects
-Types of Acute Dystonia
A
- Occulojiro crisis – Eyes turned up in the head
2. Tordecolis - whole body contracts upwards
14
Q
Anti-Psychotic Side Effects
-Neuroleptic Malignant Syndrome
A
- Idiosyncratic reaction to neuroleptic meds
- Pt has:
- FEVER, muscular rigidity, altered mental status, autonomic dysfunction - Cure is to stop anti-psychotic
