Lecture 3 Dermatomes & Mytomes Flashcards
What is each neural segment called and what do they associate with/give rise to?
Neural level.
-contribute to the dermatomes and myotomes within upper and lower limbs
What contains the precursor cells of the nervous system?
Neural tube
How does the neural tube and somites form?
- at 18 days
- neural plate starts to invaginate forming the neural groove
- eventually the neural folds approach each other where they meet in the midline and fuse forming the neural tube
- by day 24
- the cephalic (head) and caudal (tail) have closed
- from day 20 onwards paired somites appear
What do somites form and how many are there?
- day 30: there are 34-35 pairs of somites
- as soon as they form they start to differentiate
- differentiate into the sclerotome and the dermatomyotome
What does the sclerotome give rise to?
vertebrae and ribs (ventral)
What does the dermatomyotome give rise to?
Dermis and muscle (dorsal)
What are dermatomyotomes?
They develop in association with a specific neural level and take their nerve supply from the neural tube as a spinal nerve.
Why would skin and muscle have a common spinal nerve supply?
The skin and muscle are derived from a single dermatomyotome.
What is a dermatome?
Area of skin that is supplied by a single spinal nerve.
What map do you use to know the anatomical distributiom of dermatomes?
Foerster Dermatome Map
e.g. T4/T5:nipples, T10:umbilicus, L1:groin
Where does the axon of a nerve arise from?
The axon hillock.
What is the structure of a peripheral nerve?
- each nerve fibre/axon is surrounded by the endoneurium
- perineurium surrounds each fascile (bundle of nerve fibres)
- epineurium surrounds the entire peripheral nerve
What does the endoneurium secrete?
Endoneurial fluid, which surrounds each fibre.
- this increases during nerve irritation or injury.
- this oedema in the nerve can be detected by an MRI
What is the function of the endoneurium and what is it made from?
Consists of an inner sleeve of material called the glycocalyx and a mesh of collgen.
-prevents certain molecules passing from blood into endoneurial fluid
What are vasa nervorum?
Nerves with high metabolic rates contain their own blood vessels in epineurium.
What is a spinal nerve?
A MIXED nerve that carries motor & sensory signals b/w the body and spinal chord.
-they are short and exist briefly as they pass through the intervertebral foramen (marks the difference b/w CNS and PNS)
What is a dorsal root?
Contain afferent, sensory nerve fibres ONLY.
What is a ventral root?
Contain efferent motor, autonomic nerve fibres ONLY.
How many pairs of spinal nerves are there?
31 (each pair leave out either side of the intervertebral foramina and branch into the rami)
What is each vertebra derived from?
2 adjacent somites (above and below)
What does the spinal chord run through?
Vertebral foramen (intervertebral foramina allow spinal nerves to leave)
Where does the spinal chord commence and end?
Inferior margin of medulla oblongata, at base os brain stem, and ends at the conus medullaris at L1/2
Why are the spinal chord segments not in line with the vertebrae?
Differential growth. The growth of the spinal chord is much slower than the rest of the body, so is shorter.
What is inferior/superior meaning?
Inferior is closer to bottom of body
Superior is closer to the top of the body