Lecture 3 - Cells and Tissues of the Immune System 2

Question 1

Four paradigms of the immune system

Answer 1

1) Immune recognition
2) Immune effector function
3) Immune regulation
4) Immune memory

Question 2

Is inside the mouth inside the body?

Answer 2

No

Question 3

Definition of ‘inside the body’

Answer 3

When the epithelial barrier has been surpassed

Question 4

Cardinal signs of inflammation
1)
2)
3)
4)
5)

Answer 4

1) Dolor
2) Calor
3) Rubor
4) Tumor
5) Function laesia

Question 5

What is cognate interaction?

Answer 5

Interaction between antigen-presenting cell and naive T cell bearing receptor for presented antigen

Question 6

Structure of naive T cell Vs activated T cell

Answer 6

Naive T cell is mostly nucleus

Activated T cell has more cytoplasm, denser nucleus

Question 7

Immunopathology

Answer 7

Damage to body from immune response

Question 8

Example of immunopathology

Answer 8

Hepatitis
Hepatitis doesn’t damage host hepatocytes
CD8+ response to hepatitis infection is what causes damage

Question 9

Innate immune effector mechanisms
1)
2)
3)

Answer 9

1) Phagocytosis
2) Microbicidal agents
3) Complement

Question 10

How are the innate and adaptive immune systems bridged?

Answer 10

1) Dendritic cell phagocytoses antigen
2) Travels to local lymph node
3) Presents to naive T cells

Question 11

Antibody functions
1)
2)
3)

Answer 11

1) Neutralisation of toxins
2) Opsonisation
3) Complement activation

Question 12

Stages of T cell immune response
1)
2)
3)

Answer 12

1) Expansion
2) Contraction
3) Memory

Question 13

What occurs during T cell contraction?

Answer 13

Dying off of clonally-expanded T cells

Question 14

What is opsonisation?

Answer 14

Marking of objects for phagocytosis