Lecture 3: ABXs Flashcards
MC bacterial cause of Pharyngitis
MC bacterial cause of Pharyngitis = GAS
Pt presents w/ sudden onset of sore throat, fever, tonsillar inflam and exudates and anterior cervical adenopathy but no cough.
Dx?
1st line Tx? and for how long ?
Dx = Bacterial Pharyngitis (GAS)
Tx = PCN V for 10 days
Pharyngitis Tx
- ABX tx for kids
- Tx if PCN allergic
Pharyngitis Tx
- ABX tx for kids = Amoxicillin
- Tx if PCN allergic = Macrolide (mycins) –> clinda, Azithro
What is the MC bacterial cause of UTIs
MC bacterial cause of UTIs = E. coli
UTI Dx
- Common dx test
- Definitive Dx
UTI Dx
- common dx test = UA
- Defintive Dx test = Urine culture (CLEAN CATCH)
Pt presents w/ c/o burning while peeing, increased freq and urgency. On you UA you note + nitrites and leuk esterases
Dx?
1st line Tx?
Dx = UTI
1st line Tx = Nitrofurantin
- Fluroquinolones
- Bactrim
What is typicall Txs for UTIs in pregnant women
Preg women w/UTI –> Amox or Augmentin
How to Dx Otitis Media
H&P
What is the MC bacterial cause of Otitis Media
what is AOM (bacterial) usually preceded by?
Strep pneumo = MC bacterial cause of Otitis Media
- others = H. influ, M. catarralis
- AOM usually preceded by viral URI
16 mo old pt presents w/ fever, ear pain and tugging or R ear, hearing loss in R ear and stuffiness. On exam you see a bulging TM w/effusion.
Dx & 1st line Tx
Dx = Otitis Media
1st line = Amoxicillin
What is the tx of AOM if pt had recent ABX therapy (2 options)
Tx of AOM if pt had recent ABX therapy
- Augmentin
- Oral Cephalosporin
Bacterial Meningitis:
MC cause in < 1 mo
Bacterial Meningitis:
MC cause in < 1 mo = GBS
Bacterial Meningitis:
MC cause in 1 mo - 18 y/o
Bacterial Meningitis:
MC cause in 1 mo - 18 y/o = Neisseria Meningiditis
Bacterial Meningitis:
MC cause in 18 - 50 y/o
Bacterial Meningitis:
MC cause in 18 - 50 y/o = Strep Pneumo
Bacterial Meningitis:
Causes in > 50
Main cause in immunocompromised
Bacterial Meningitis:
Causes in > 50 = Listeria, S. pneumo
Main cause in immunocompromised = Listeria
What ABX must add on for pts > 50 or immunocompromised (cover listeria)
pts > 50 or immunocompromised (cover listeria)
- Ampicillin
26 y/o pt presents w/ fevers and chills, HA, neck stiffness, photsensitivity and N/V. On exam she is (+) for Kernig’s and Brudzinki’s
Dx?
Tx (for this age group)
Dx = Bacterial Meningitis
Tx for age group
- Cefotaxime or Ceftriaxone + Vanco
What is the Tx for Bacterial Meningitis in < 1 mo old
3 drugs
Tx for Bacterial Meningitis in < 1 mo old
- Ampillicin + Cefotaxime + Gentamycin
Dx Bacterial Meningitis
- What should you do before LP
- What is the definitive way to Dx
Dx Bacterial Meningitis
- CT before LP
- definitive way to Dx = CSF examination
Dx Bacterial Meningitis: LP
- how does sample look
- opening pressure level?
- protein levels?
- glucose levels?
Dx Bacterial Meningitis: LP
- how does sample look = turbid
- opening pressure level = HIGH
- protein levels =HIGH
- glucose levels = low
Dx Bacterial Meningitis: LP
- how does sample look
- opening pressure level?
- protein levels?
- glucose levels?
Dx Bacterial Meningitis: LP
- how does sample look = turbid
- opening pressure level = HIGH
- protein levels =HIGH
- glucose levels = low
Are postOp fevers likely infectious the day of infxn
NO postOp fevers NOT likely infectious the day of infxn
- usually few days after infxn
PosOp wound infections
- what are the most common causes (group)
- how to dx it
PosOp wound infections
- most common causes = Gram + bacteria (staph a, strep, enterococci)
- dx = wound gram stain + culture
- 1st gen ceph
- Clindamycin
- Augmentin
- Dicloxacillin
why are these good choices for Tx of PosOp wound infections
- 1st gen ceph
- Clindamycin
- Augmentin
- Dicloxacillin
good choices for Tx of PosOp wound infections b/c have gram + coverage
Vaginal infection ABX Tx
- For Chlamydia
- For Gonorrhea
- For Candida
- BV or Trichomonas
Vaginal infection ABX Tx
- For Chlamydia –> 1g Azithro
- For Gonorrhea –> Ceftriax (IM) + Azithro
- For Candida –> Fluconazole
- BV or Trichomonas –>Metronidazole
Genital lesions Dx
Dx test for Syphilis
How to Dx HSV
Genital lesions Dx
Syphilis = RPR
HSV = cultures
Genital lesions
- Tx for Syphilis
Genital lesions
- Tx for Syphilis = PCN G (IM)
Genital lesions
- Tx for Chancroid (2 options)
Genital lesions
- Tx for Chancroid = Ceftriaxone or Azithromycin
Genital lesions
- Tx for LGV or Granuloma inguinale
Genital lesions
- Tx for LGV or Granuloma inguinale = Doxy or Azithromycin
Infectious Diarrhea
- Tx for C.diff (2 options)
Infectious Diarrhea
- Tx for C.diff = PO Vanco or Metronidazole
Infectious Diarrhea
- Tx for Camplobacter, Salmonella, or Shigella
Infectious Diarrhea
- Tx for Camplobacter, Salmonella, or Shigella = Quinolone
Infectious Diarrhea
- Tx for Giardia
Infectious Diarrhea
- Tx for Giardia = Metronidazole
Sinusitis
- MC cause of Acute
- MC cause of Chronic
- MC fungal cause
Sinusitis
- MC cause of Acute = S. Pneumo
- MC cause of Chronic = Staph aureus
- MC fungal cause = Aspergillus
Dx Sinusitis
1. What is the ToC for diagnosing it?
Dx usually clinical
Dx Sinusitis
1. What is the ToC for diagnosing it = CT
Dx usually clinical
Pt presents w/ Ha, malaise, nasal d/c and
sinus pain and pressure that is worse w/bending down and leaning forward. Sxs for past 3 weeks. On exam you see opaqueness w/transillumination.
Dx + 1st line Tx?
Dx = ACUTE Sinusitis
1st line Tx = Augmentin
Bronchitis
- MC cause viral or bacterial
- if > 14 days of cough what is likely cause
Bronchitis
- MC cause = viral (adeno esp)
> 14 days of cough –> pertussis (Bordella)
Bronchitis
- is mainstay of treatment supportive or ABX
Bronchitis
- mainstay of tx = supportive
Supportive Tx of bronchitis
NSAIDs, expectorant or cough suppressant
inhaled bronchodilators
When should you consider ABX tx for bronchitis
consider ABX tx for bronchitis if pt not better after 1 wk of supportive Tx
2 ABX Tx options for bronchitis
2 ABX Tx options for bronchitis
- Macrolides
- Azithromycin
2 ABX Tx options for bronchitis
2 ABX Tx options for bronchitis
- Macrolides
- Azithromycin
Pt presents w/ productive cough for the past week. He recently had a cold but that has since resolved.
Dx?
Bronchitis
2 ABX Tx options for bronchitis
2 ABX Tx options for bronchitis
- Macrolides
- Doxy