lecture 3 Flashcards

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1
Q

Mendell

A
  • basic principle in heredity of breeding garden peas
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2
Q

Experiment of peas

A
  • pea plants available in many variets with distinct heritable features (different traits)
  • strictly control whihc plants mated
  • male a female organs for each plant
  • true breeding = plants self pollinate (offspring with same trait)
  • hybridisation (cross pollination)
  • P generation, hybrid F1 generation
  • self pollinate for F2
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3
Q

Law of segregation

A
  • two alleles for character separated during formation of gametes
  • blending model correct then F1 self-fertilise, F2 generation include purple/white plants
  • white absent in F1
  • ratio 1 white to 3 purple F2
  • purple dominant, white recessive
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4
Q

Mendell hypothesis

A
  • alternative versions of genes account for variations inherited
  • each character, an organism inherits two alleles (1 from each parent)
  • if alleles at locus differ, one dominant allele determines organisms appearance. Other recessive allele no noticable effect on appearance
  • law of segregation, two alleles for a heritable character separate and segregate during gamete production and end up in different gemetes
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5
Q

MH 1

A
  • two colour versions of flower in peas (purple white)
  • alternate versions called alleles
  • gene resides at specific locus on specific chromosome
  • DNA at locus can vary sequence nucleotides
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6
Q

MH 2

A
  • diploid inherited one set of chromosomes from each parent
  • diploid homologous pair (two copies of each gene)
  • homologous loci may be identical
  • or two alleles may differ
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7
Q

MH 3

A
  • in flower colour eg. F1 plants inherited purple allele from on parent and white allele from other
  • purple is dominant therefore flower is purple
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8
Q

MH 4

A
  • segregation of alleles correspond to distribution of homologous chromosomes to different gemetes in meiosis
  • two identical alleles = allele present as single copy in all gemetes
  • different alleles = 50% gametes recieved each type of allele
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9
Q

terminology

A
  • homozygous = identical alleles
  • heterozygous = different alleles
  • phenotype = organism’s traits
  • genotype = genetic makeup (two organisms may have same phenotype but different genotype: hetero/homozygous)
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10
Q

law of independent assortment

A
  • each pairof elleles segregate independently into gametes
  • for experiment F1 progeny produced monohybrids (heterozygous for 1 character)
  • dihybrid cross (inheritence of seed colour/shape); - alleles segregate independently due to phenotypes (yellow/green/wrinkled) not being just yellow (implying staying together)
  • 4 classes of alleles from each ova and sperm = 16 probable ways
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11
Q

Laws of probability

A
  • laws of segregation reflect probability
  • multiplication rule (multiply iindividual probabilities); also applies for dihybrid crosses
  • rule of addition (sum of separate probabilities)
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12
Q

particulate behavious of genes

A
  • can predict probability having specific genotype/phenotype but not for any particular seed
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13
Q

inheritance patterns v

A

-

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